Validity and Safety of Robot-Assisted Laparoscopic Radical Cystectomy for the Elderly: Results of Perioperative Outcomes in Patients Aged ≥80 Years

Tanabe, Kenji; Nakanishi, Yasukazu; Umino, Yosuke; Okubo, Naoya; Kataoka, Masao; Yajima, Shugo; Masuda, Hitoshi

doi:10.5152/tud.2022.22099

Cited by 4 publications

(7 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Tanabe et al. reported a significantly higher incidence of perioperative complications of all grades in patients with CCI ≥3 20 . Our study showed that CCI ≥2 may be a risk factor for perioperative complications ≥grade 3.…”

Section: Discussionsupporting

confidence: 56%

“…Tanabe et al reported a significantly higher incidence of perioperative complications of all grades in patients with CCI ≥3. 20 Our study showed that CCI ≥2 may be a risk factor for perioperative complications ≥grade 3. CCI has long been used as a predictor of postoperative complications in a variety of areas and may be equally useful in RARC.…”

Section: Discussionmentioning

confidence: 57%

See 1 more Smart Citation

Chronic kidney disease and Charlson comorbidity index predict complications after robot‐assisted radical cystectomy: A single‐center study in Japan

Matsukawa,

Morizane,

Shimizu

et al. 2023

Int J of Urology

View full text Add to dashboard Cite

ObjectivesTo investigate preoperative patient factors that may predict the occurrence of perioperative complications following robot‐assisted radical cystectomy at a single center in Japan.MethodsFrom 2013 to 2022, 103 patients underwent RARC at our institution. Complications within 90 days after surgery were assessed using the Clavien–Dindo classification. Preoperative characteristics and surgical outcomes were compared between cohorts with and without complications ≥grade 3. Logistic regression analysis was used to identify the risk factors associated with perioperative complications.ResultsOverall, 27% of patients (27/103) experienced grade 3 or higher complications. The cohort that developed complications ≥grade 3 exhibited significantly higher Charlson comorbidity index (p = 0.046) and significantly lower estimated glomerular filtration rate (p = 0.048). Charlson comorbidity index ≥2 (p = 0.037) and estimated glomerular filtration rate <53 (p = 0.008) were independent predictors for the occurrence of complications ≥grade 3. The incidence of complications ≥grade 3 was 61.5% in the group possessing both factors, which was significantly higher than those in the groups possessing neither factor nor only one of the two factors.ConclusionsOur results suggest that the Charlson comorbidity index and preoperative estimated glomerular filtration rate may be predictors of perioperative complications. It is important to evaluate the patient's preoperative characteristics and choose the surgical procedure accordingly.

show abstract

Section: Discussionsupporting

confidence: 56%

Section: Discussionmentioning

confidence: 57%

Chronic kidney disease and Charlson comorbidity index predict complications after robot‐assisted radical cystectomy: A single‐center study in Japan

Matsukawa,

Morizane,

Shimizu

et al. 2023

Int J of Urology

View full text Add to dashboard Cite

show abstract

“…Radical cystectomy is the standard treatment for muscle‐invasive bladder cancer and selected high‐risk non‐muscle‐invasive bladder cancer patients across all age groups 1–3 . Nevertheless, several problems, including surgical invasiveness, perioperative complications, and disease‐specific mortality, were reported in radical cystectomy 4–6 . Although laparoscopic radical cystectomy (LRC) has been implemented to reduce surgical invasiveness, the surgical outcomes have remained controversial among older patients 7,8 .…”

Section: Introductionmentioning

confidence: 99%

“…Recently, robotic‐assisted radical cystectomy (RARC) has become a standard minimally invasive radical cystectomy 9,10 . Studies have previously shown the positive outcomes of radical cystectomy in patients aged 80 or above, 5,6,11,12 while Groote et al 2 . reported significantly higher cancer‐specific mortality in octogenarians who received RARC.…”

Section: Introductionmentioning

confidence: 99%

“…[1][2][3] Nevertheless, several problems, including surgical invasiveness, perioperative complications, and diseasespecific mortality, were reported in radical cystectomy. [4][5][6] Although laparoscopic radical cystectomy (LRC) has been implemented to reduce surgical invasiveness, the surgical outcomes have remained controversial among older patients. 7,8 Recently, robotic-assisted radical cystectomy (RARC) has become a standard minimally invasive radical cystectomy.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Surgical outcomes of robot‐assisted radical cystectomy in octogenarian or older patients: A Japanese nationwide study

et al. 2023

View full text Add to dashboard Cite

ObjectiveTo evaluate the surgical outcomes of robot‐assisted radical cystectomy (RARC) in octogenarian or older patients based on a Japanese nationwide database.MethodsThe diagnosis procedure combination database was used to extract the data on radical cystectomy cases. Surgical outcomes of RARC in octogenarian or older patients (older group) were initially compared to those of patients younger than 80 years (younger group). Then, the surgical outcomes of RARC in the older group were compared to those of open radical cystectomy (ORC) and laparoscopic radical cystectomy (LRC) in the same age group.ResultsBetween 2018 and 2021, 478 RARC cases in the older group and 2257 RARC cases in the younger group were identified. In the older group, ileal conduit, neobladder, and other urinary diversions were carried out in 352 (73.6%), 22 (4.6%), and 104 (21.8%) patients, respectively. In the older group, when compared with the younger group, the complication rate (24.9%), blood transfusion rate (41.4%), and in‐hospital mortality (1.4%) were equivalent, while significantly shorter anesthesia time and longer length of stay were observed in the older group (521.0 ± 140.4 min vs. 595.1 ± 141.71 min, p < 0.01, and 32.9 ± 16.8 days vs. 30.6 ± 17.8 days, p = 0.01, respectively). In the comparison of the surgical outcomes of older patients receiving RARC to those receiving ORC (n = 746) and LRC (n = 375), the RARC group had the lowest complication rate and the shortest length of stay, while the shortest anesthesia time was noted in the ORC group.ConclusionThe feasibility of RARC for octogenarian or older patients was demonstrated by the nationwide database study.

show abstract

Utility and safety of robot-assisted radical cystectomy in older patients with bladder cancer

Kumada,

Nakane,

Yamada

et al. 2023

Minimally Invasive Therapy & Allied Technologies

View full text Add to dashboard Cite

Validity and Safety of Robot-Assisted Laparoscopic Radical Cystectomy for the Elderly: Results of Perioperative Outcomes in Patients Aged ≥80 Years

Cited by 4 publications

References 24 publications

Chronic kidney disease and Charlson comorbidity index predict complications after robot‐assisted radical cystectomy: A single‐center study in Japan

Chronic kidney disease and Charlson comorbidity index predict complications after robot‐assisted radical cystectomy: A single‐center study in Japan

Surgical outcomes of robot‐assisted radical cystectomy in octogenarian or older patients: A Japanese nationwide study

Utility and safety of robot-assisted radical cystectomy in older patients with bladder cancer

Contact Info

Product

Resources

About