Validity and reliability of a revised Japanese version of the Arthritis Impact Measurement Scales version 2 (AIMS2)

Sato, Hajime; Hashimoto, Akira; Araki, Shunichi; Nishibayashi, Yasuro; Hoshi, Keiko; Kutsuna, Tastuo; Shiino, Yasuaki; Ishihara, Yasuhiro; Tsuboi, Seiji; Fujimori, Juro; Kondo, Hirobumi; Akizuki, Masashi; Möroi, Y; Yoshida, Shunji; Yokoyama, Kazuhito

doi:10.3109/s101650070011

Cited by 5 publications

(4 citation statements)

References 17 publications

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“…As mentioned above, we have explained patient’s health status based on subjective scales. Recently, health status scales such as SF-36 49 ) and the Arthritis Impact Measurement Scales, version 2 (AIMS2) 50 ) have been validated in a Japanese population and may be available in Japan. A quality of life scale for Japanese patients with intractable disease including SLE was also developed 51 ) .…”

Section: Discussionmentioning

confidence: 99%

Psychological Profiles and Health Status in Japanese Female Patients with Systemic Lupus Erythematosus: The Miyagi Lupus Collaborative Study.

Minami

Sasaki

Arai

et al. 2002

Journal of Epidemiology

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and The Miyagi Lupus Study Group 6 Psychological factors have been suspected to be associated with the development of systemic lupus erythematosus (SLE) and patients health status. However, psychological profiles among Japanese patients with SLE have been poorly understood. We started a prospective study of female patients with SLE in 1995. Using the baseline data from 279 patients in this prospective study, we cross-sectionally analyzed the relations of clinical factors and social factors to psychological factors, and the association between psychological factors and mental and physical health status. We used the Japanese notion ikigal as an indicator of mental health, and ambulatory activity as an indicator of their physical health, respectively.To measure psychological factors, the short-form of the Eysenck Personality Questionnaire-Revised (short EPQ-R) and the Multidimensional Health Locus of Control (HLOC) scale were used. Active phase of the disease was significantly related to the neuroticism score in the short EPQ-R. Educational level was inversely related to the scores of powerful others and chance HLOC belief. As for health status, the internal HLOC belief was significantly associated with /k/gal and the chance HLOC belief was inversely associated with ambulatory activity. The scores on the short EPQ-R (Extraversion/lntroversion and Neuroticism) were exclusively related to ikigai. This study suggests that psychological factors may have effects on both the development of SLE and patients health status.

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Section: Discussionmentioning

confidence: 99%

Psychological Profiles and Health Status in Japanese Female Patients with Systemic Lupus Erythematosus: The Miyagi Lupus Collaborative Study.

Minami

Sasaki

Arai

et al. 2002

Journal of Epidemiology

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“…The Arthritis Impact Measurement Scales (AIMS) have been widely used to assess the health status of people with arthritis in many countries for years (1–9). Extensive testing and refinement have been done to make AIMS a reliable, valid, and sensitive tool for evaluating the health status of individuals with arthritis (1, 10–12).…”

Section: Introductionmentioning

confidence: 99%

Translation and validation of Arthritis Impact Measurement Scales 2 into Chinese: CAIMS2

Chu

Chiu

Wong

et al. 2004

Arthritis & Rheumatism

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Objective. To evaluate the validity, reliability, and cultural relevance of the Arthritis Impact Measurement Scales 2 (AIMS2) as a health assessment tool for Chinese-speaking patients with arthritis. Methods. The cultural relevance, language equivalency, and content validity of the AIMS2, Chinese version (CAIMS2) were evaluated by an expert panel. Measurement performance was tested on 240 subjects (rheumatoid arthritis ‫؍‬ 81, osteoarthritis ‫؍‬ 77, healthy ‫؍‬ 82). Subjects (n ‫؍‬ 175) were retested within 2 weeks for testing of reliability. Results. Three items were modified and 2 items were added, as suggested by the expert panel. Interitem reliability was satisfactory (intraclass correlation coefficient 0.8552-0.9594). Test-retest reliability of the CAIMS2 subscales ranged from 0.770 to 0.952 in subjects in whom the CAIMS2 was self administered. Significant score differences between patients with arthritis and healthy subjects were found in all 12 subscales, except for the support from family and friends and tension subscales. CAIMS2 subscale scores correlated with clinical and laboratory measures of disease activity and patients' perceived quality of life as measured using the INTRODUCTIONThe Arthritis Impact Measurement Scales (AIMS) have been widely used to assess the health status of people with arthritis in many countries for years (1-9). Extensive testing and refinement have been done to make AIMS a reliable, valid, and sensitive tool for evaluating the health status of individuals with arthritis (1,10 -12). Previous studies evaluating the efficiency and sensitivity of existing health status measures have demonstrated that the AIMS was efficient in assessing patients' mobility, pain level, and global functional impairment (13). In 1992, Meenan et al (14) further revised the measure (AIMS2) to cover aspects of arthritis relevant health status-arm function, work, and support from family and friends-that were not addressed by the previous measure. Three sections were also added to assess the respondents' satisfaction with current level of function, problem areas, and areas in which they wanted improvement. Empirical data supported that the AIMS2 is valid and reliable.Chinese people make up almost one-quarter of the world's population. Han Chinese made up 93.5% of the population in the People's Republic of China where Mandarin is the official language. Although there are 201 living languages (dialects) in China, the people in China share a unified writing system (Ethnologue.com, 2002). Recently, health status measures, such as the Short Form 36, Health Assessment Questionnaire, and the World Health Organization Quality of Life instrument (WHOQOL-BREF), have been translated and validated for Chinese-speaking patients (15-17). However, these general questionnaires are not as comprehensive, sensitive, or specific as the AIMS2 in detecting health changes in arthritis patients (13). The aim of this study was therefore to translate AIMS2 into Chinese (CAIMS2) and evaluate its validity. SUBJECTS AND METHODS

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“…13) AdoHcy potentiates tumor necrosis factor-induced cytotoxicity in human breast carcinoma cells, and is a competitive inhibitor of histone lysine methyltransferase in rat brain. 14,15) A recent report has suggested that histone H3 lysine 9 methylation is inhibited by increasing concentrations of AdoHcy. 16) Protein arginine methyltransferases such as PRMTs can be inhibited by another intermediate molecule in the methylation pathway, adenosine dialdehyde (AdOx).…”

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confidence: 99%

Gene Expression Analysis in Human Gastric Cancer Cell Line Treated with Trichostatin A and S-Adenosyl-L-homocysteine Using cDNA Microarray

Lee

Park

Yang

et al. 2004

Biological & Pharmaceutical Bulletin

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Trichostatin A (TSA) and S-adenosyl-L-homocysteine (AdoHcy) have been reported to affect histone modifications. To investigate the effects of two drugs that can reportedly affect chromatin remodeling, we analyzed the gene expression profiles of TSA and AdoHcy in a gastric cancer cell line using 14 K cDNA microarray. The significant analysis of microarray (SAM) identified 98 and 43 differentially expressed genes in TSA and AdoHcy treated sets, respectively, and selected genes were functionally classified. In the gastric cancer cell line, genes related to cell communication, cell growth/maintenance, and morphogenesis were highly expressed with TSA, and genes with cell growth/maintenance, metabolism, oxidoreductase activity were upregulated with AdoHcy. Genes downregulated with TSA included those controlling the cell cycle, cell growth/proliferation, DNA binding, and metabolism, whereas genes involved in calcium signaling, cell growth/proliferation, and metabolism were downregulated with AdoHcy. Furthermore, we identified the genes commonly expressed in both drug treatments. Compared to TSA, AdoHcy did not induce apoptosis in the SNU-16 gastric cancer cell line, and RT-PCR was performed for selective genes to confirm the microarray data. This gene expression profile analysis with TSA and AdoHcy should contribute to a greater understanding of the molecular mechanism of chromatin remodeling and cancer, and provide candidate genes for further studies involving the roles of histone modifications in gastric cancer.

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Validity and reliability of a revised Japanese version of the Arthritis Impact Measurement Scales version 2 (AIMS2)

Cited by 5 publications

References 17 publications

Psychological Profiles and Health Status in Japanese Female Patients with Systemic Lupus Erythematosus: The Miyagi Lupus Collaborative Study.

Psychological Profiles and Health Status in Japanese Female Patients with Systemic Lupus Erythematosus: The Miyagi Lupus Collaborative Study.

Translation and validation of Arthritis Impact Measurement Scales 2 into Chinese: CAIMS2

Gene Expression Analysis in Human Gastric Cancer Cell Line Treated with Trichostatin A and S-Adenosyl-L-homocysteine Using cDNA Microarray

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