Validation of viscoelastic coagulation tests during cardiopulmonary bypass: comment

Solomon, Cristina; Fickenscher, Karl; Ormonde, Lucindo; Ranucci, Marco

doi:10.1111/jth.13122

Cited by 3 publications

(2 citation statements)

References 20 publications

(23 reference statements)

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“…The assays are highly correlated but not completely inter-changeable, this is in part due to the sample substrate being whole blood in VCA and platelet-poor plasma in the Clauss, and when comparing VCAs, there are additional mechanical and methodological reasons that affect the torsion force to millimeter translation in the plot, and whether or not there is possible residual platelet contribution to the amplitude even after addition of the above reagents. 23 , 24 …”

Section: Contrasting Techniques For Determining Fibrinogen Level In Vmentioning

confidence: 99%

Acquired hypofibrinogenemia: current perspectives

Besser¹,

MacDonald²

2016

JBM

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Acquired hypofibrinogenemia is most frequently caused by hemodilution and consumption of clotting factors. The aggressive replacement of fibrinogen has become one of the core principles of modern management of massive hemorrhage. The best method for determining the patient’s fibrinogen level remains controversial, and particularly in acquired dysfibrinogenemia, could have major therapeutic implications depending on which quantification method is chosen. This review introduces the available laboratory and point-of-care methods and discusses the relative advantages and limitations. It also discusses current strategies for the correction of hypofibrinogenemia.

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Section: Contrasting Techniques For Determining Fibrinogen Level In Vmentioning

confidence: 99%

Acquired hypofibrinogenemia: current perspectives

Besser¹,

MacDonald²

2016

JBM

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“…We would like to thank Solomon et al . for their interest in our study and for elucidating further the major differences in heparin sensitivities of the Clauss assay, dependent on reagent manufacturer .…”

mentioning

confidence: 99%

Validation of viscoelastic coagulation tests during cardiopulmonary bypass: reply

Ortmann

Klein

Besser

2015

Journal of Thrombosis and Haemostasis

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Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients

Fabbro

Gutsche

Miano

et al. 2016

Anesthesia &Amp; Analgesia

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Our results revealed negligible change in FLEV values from the rewarming to postbypass periods, with a CI that does not include clinically meaningful differences. These findings suggest that rewarming samples could be utilized for ordering fibrinogen-specific therapies before discontinuation of CPB. Mean FLEV values were consistently higher than the reference standard at each time point. Moreover, bias was highly heterogeneous among samples, implying a large range of potential differences between assays for any 1 patient.

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Validation of viscoelastic coagulation tests during cardiopulmonary bypass: comment

Cited by 3 publications

References 20 publications

Acquired hypofibrinogenemia: current perspectives

Acquired hypofibrinogenemia: current perspectives

Validation of viscoelastic coagulation tests during cardiopulmonary bypass: reply

Comparison of Thrombelastography-Derived Fibrinogen Values at Rewarming and Following Cardiopulmonary Bypass in Cardiac Surgery Patients

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