Validation of the Revised Patient Perception of Migraine Questionnaire (PPMQ-R): Measuring Satisfaction with Acute Migraine Treatment in Clinical Trials

Abstract

This study was aimed to evaluate in clinical trial settings the psychometric properties of the revised Patient Perception of Migraine Questionnaire (PPMQ-R), a satisfaction measure for acute migraine treatment. The PPMQ-R was administered 24 h post dosing in 1304 migraineurs randomized to two identical Phase 3, single-attack trials. Reliability, concurrent and construct validity and known-groups validity were evaluated using Cronbach's alpha, Pearson correlations and analysis of variance, respectively. PPMQ-R scale and Total scores (Efficacy, Functionality and Ease of use) showed very good internal consistency reliability (alpha 0.84-0.99). Efficacy, Functionality and Total PPMQ-R scores showed large, inverse relationships with migraine pain severity, number of migraine symptoms and work ability (r = -0.62 to -0.75; all P < 0.0001). All scales discriminated among migraine pain severity levels (all P < 0.001). The PPMQ-R has sufficient evidence of validity and reliability for measuring patient satisfaction, an important benchmark of quality and effective care.

Factors Associated With Discharge After Initial Emergency Treatment of Pediatric Migraine

“…Although pain scores have been shown to be well correlated with quality-of-life measures 17 and treatment efficacy in migraineurs, 18 pain scores did not seem to be a significant consideration in initial medication selection in the ED in our data set (Tables 3 and 4). Our results suggest that, in addition to other patient characteristics, physicians may also be able to use arrival pain scale to help select migraine treatment ( Table 7, Fig.…”

Consistency of Return to Normal Function, Productivity, and Satisfaction Following Migraine Attacks Treated With Sumatriptan/Naproxen Sodium Combination

“…Participants completed the Patient Perception of Migraine Questionnaire‐Revised (PPMQ‐R), a valid, reliable, and responsive measure, at 24 hours postdosing in each of 4 attacks. Subjects were instructed to assess only the study medication taken for that migraine.…”

The Development of a Survey to Measure Completeness of Response to Migraine Therapy

“…Additionally, the participants in this study completed the HIT‐6 at baseline, 9 the PPMQ‐R at BL and EOS, 11 and a migraine diary for each migraine experienced during the 2‐month study period.…”

“…(The EOS CORS is identical to the BL CORS except that it refers to "the study migraine treatment" rather than "your current migraine treatment.") Additionally, the participants in this study completed the HIT-6 at baseline, 9 the PPMQ-R at BL and EOS, 11 and a migraine diary for each migraine experienced during the 2-month study period.…”