Validation of the PHQ-9 depression scale in Ethiopian cancer patients attending the oncology clinic at Tikur Anbessa specialized hospital

Degefa, Mikyas; Dubale, Benyam Worku; Bayouh, Fikirte Girma; Ayele, Biniyam A.; Zewde, Yared Zenebe

doi:10.1186/s12888-020-02850-3

Cited by 29 publications

(33 citation statements)

References 28 publications

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“…The 9-item Patient Health Questionnaire (PHQ-9) was used to assess depression symptoms. The questionnaire was validated and developed by the local language, Afaan Oromo and Amharic language in the Ethiopian context and it recommended for use (31,32).…”

Section: Data Collection and Questionnairementioning

confidence: 99%

Magnitude and Predictors of Health Care Workers Depression During the COVID-19 Pandemic: Health Facility-Based Study in Eastern Ethiopia

2021

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Background: Depression of health care workers was related to work absences, resignations, and poor work performance, affecting the quality of patient care and the health care system. The Coronavirus disease pandemic has had an effect on the mental health of health care workers. Health care workers are facing challenges that can be stressful, overwhelming, and cause strong emotions, may put them at higher risk to develop depression. There is limited evidence that assesses health care workers' depression and its associated factors in the study area during the Coronavirus disease pandemic. Therefore this study aimed to assess depression and associated factors among health care workers in eastern Ethiopia.Method: The cross-sectional study design was conducted from October 26th to November 15, 2020. A total of 265 health care workers from 10 health facilities participated. Patient Health Questionnaire was used for the collection of depressive symptoms. The data were analyzed by using STATA version 14 software. To assess the association between depression and the predictors Adjusted Odds Ratio along with a 95% confidence interval was estimated by using logistic regression analysis. A statistical significance was declared at p-value ≤ 0.05.Results: Of the total 265 study participant, 176 (66.4%) and 95% CI: 60.4%, 71.8% of them reported depressive symptoms. Of 176 reported symptoms of depression 27.9, 24.1, 9.4, 3.7, and 1.1% were had minimal, mild, moderate, moderate-severe, and severe depressive symptoms respectively. The multivariable logistic regression analysis revealed the odds of depression were 2.34 times higher among female participants compared to male participants (AOR: 2.34, 95%CI: 1.09-5.02). In addition, the odds of depression for participants who perceived susceptibility to COVID-19 was 4.05 times higher among their counterpart (AOR: 4.05, 95%CI: 1.12-14.53).Conclusions: Health care workers who experienced depression in the study was high. Health care workers' mental health needs to be protected during the COVID-19 pandemic. Female health care workers and health care workers perceived susceptibility of COVID-19 need attention.

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Section: Data Collection and Questionnairementioning

confidence: 99%

Magnitude and Predictors of Health Care Workers Depression During the COVID-19 Pandemic: Health Facility-Based Study in Eastern Ethiopia

2021

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“…The 9-item Patient Health Questionnaire (PHQ-9) tool was used to assess depression symptoms. The questionnaire was validated in the Ethiopian context and it recommended for use [26].…”

Section: Data Collection and Questionnairementioning

confidence: 99%

Health care workers depression and associated factors during COVID-19. Health facility-based study in Eastern Ethiopia

Yadeta

Baca

Balis

2020

Preprint

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Background Depression of health care workers was related to work absences, resignations, and poor work performance, affecting the quality of patient care and the health care system. It may be at higher risk during the Coronavirus disease (COVID-19) pandemic. There is limited evidence that assesses depression and its associated factors in the study area. Therefore this study aimed to assess depression and associated factors among health care workers (HCW) in eastern Ethiopia. Method: The cross-sectional study design was conducted from October 26th to November 10, 2020. To assess depression among health care workers. Patient Health Questionnaire (PHQ-19) questionnaire was used for the collection of depressive symptoms. The data were analyzed by using STATA version 14 software. Adjusted Odds Ratio (AOR) along with 95% CI was estimated to examine factors associated with depression symptoms using logistic regression analysis. Results Of the total 265 study participant, 176 (66.4%) and 95% CI: 60.4%, 71.8% of them reported depressive symptom. Of 176 reported symptoms of depression 27.9%, 24.1%, 9.4%, 3.7%, and 1.1% were had minimal, mild, moderate, moderate-severe, and severe depressive symptoms respectively. Being female [AOR: 3.40, (95%CI: (1.79, 6.45)], participants who perceived susceptibility to COVID-19 [AOR: 2.30, (95%CI: (1.12, 4.71)], and perceived severity to COVID-19 [AOR: 3.06, (95%CI: (1.35, 6.91)] were higher risks of experiencing depression symptoms. Participants who had work experience 3–5 years [AOR: 0.21, (95%CI: (0.08, 0.56)], and the participant who had 6–10 years’ work experience [AOR: 0.30, (95%CI: (0.11, 0. 84)] were had less likely to experience depression symptoms when compared with a participant who had two and fewer years of work experience. Conclusions A high proportion of health care workers experienced depression symptoms. Health care workers' mental health needs to be protected during the COVID-19 pandemic. Female health care workers, junior health care workers, and HCWs perceived susceptibility, and perceived severity of COVID-19 need attention.

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“…Primary exposure: depressive symptoms Depressive symptoms were measured using the Patient Health Questionnaire, 9-item version (PHQ-9) Kroenke et al, 2011]. Validity of the PHQ-9 tool in Ethiopia was investigated against the gold standard of the Mini International Neuropsychiatric Interview (MINI) diagnostic tool among cancer patients in Tikur Anbessa hospital, the national referral and teaching hospital, and showed a sensitivity of 88% and speci city of 78.1% to detect major depressive episode (MDE) [43]. Validity of the PHQ-9 for depression screening and the diagnosis was also done against psychiatrist administered semi-structure schedules for clinical assessment in neuropsychiatry (SCAN) interview among 926 Ethiopian adults in 2013 demonstrate good reliability and validity of the tool (sensitivity = 86% and speci city = 67%), Bizu Gelaye et al [44].…”

Section: Primary Outcome: Viral Load Suppressionmentioning

confidence: 99%

Virological Non-Suppression and Associated Factors Among Adolescents and Youth Living with HIV in Ethiopia: A Facility-Based Case-Control Study

Dires

Manyazewal

Charlotte

2021

Preprint

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Background: Virological non-suppression remains the major cause of treatment failure and mortality among adolescents and youth living with HIV in low- and middle-income countries (LMICs). Behavioral and mental health disorders affect adherence to antiretroviral therapy (ART) and the underlying virological suppression, but evidence from LMICs is relatively limited. We aimed to assess HIV virological non-suppression and associated factors among adolescents and youth attending ART in Ethiopia. Methods: A 1:2 matched facility-based case-control study was conducted at ALERT Hospital, Addis Ababa, Ethiopia, among patients with HIVaged 12-24 years who were on ART and with a viral load > (case) or < (control) than 1000 copies/ml after at least six months on ART. The primary outcome was viral load non-suppression: a plasma viral load > 1000 copies/ ml based on two consecutive viral load measurements every three months. The primary exposure was depressive symptoms as measured using the PHQ-9 (Patient Health Questionnaire, 9-item version). Other variables include adherence to ART and sociodemographic characteristics of participants. Data were collected using structured, blinded lay interviewer-administered questionnaires, and data extraction forms. Conditional multivariable logistic regression was conducted using STATA version 14.2 to test the main hypotheses. Results: The study enrolled 192 participants, with a median age of 18 years and 52.1% males. None of the participants reported smoking or chewing Khat (a leaf that stimulates mood). With the PHQ-9 tool, 47%, 28%, and 25% had minimal or no, probable to mild and moderate to severe depression symptoms, respectively. Having depressive symptoms is associated with a higher conditional likelihood of virological failure (odds ratio [OR] = 1.8, p < 0.001) and the association was stronger among those who have moderate or severe depressive symptoms (adjusted OR = 5, 95% CI [1.7-14.6] )and unadjusted OR = 6.8, 95% CI [3.1-14.8]). Having moderate and severe depression is associated with non-adherence to ART (adjusted OR = 10.5). Conclusion: Non-adherence to ART medications, depressive symptoms, advanced WHO stage on ART initiation, poor social support and orphan status were independently associated with virological failure among HIV-infected adolescents and youths on ART. Having moderate and severe depression has higher odds of non-adherence and virological failure. We recommend integration and task-sharing of mental health and HIV care services to reduce virological failure in this group of people.

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Validation of the PHQ-9 depression scale in Ethiopian cancer patients attending the oncology clinic at Tikur Anbessa specialized hospital

Cited by 29 publications

References 28 publications

Magnitude and Predictors of Health Care Workers Depression During the COVID-19 Pandemic: Health Facility-Based Study in Eastern Ethiopia

Magnitude and Predictors of Health Care Workers Depression During the COVID-19 Pandemic: Health Facility-Based Study in Eastern Ethiopia

Health care workers depression and associated factors during COVID-19. Health facility-based study in Eastern Ethiopia

Virological Non-Suppression and Associated Factors Among Adolescents and Youth Living with HIV in Ethiopia: A Facility-Based Case-Control Study

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