Validation of the NPI-Q, a Brief Clinical Form of the Neuropsychiatric Inventory

Kaufer, Daniel I.; Cummings, Jeffrey L.; Ketchel, Patrick; Smith, Vanessa D.; MacMillan, Audrey; Shelley, T.; López, Oscar L.; DeKosky, Steven T.

doi:10.1176/jnp.12.2.233

Cited by 1,447 publications

(1,031 citation statements)

References 24 publications

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“…The NPI-NH has high interrater reliability and has been found to be a valid instrument for the assessment of a wide range of NPS in dementia (Kat et al, 2002;Kaufer et al, 2000). The NPI-NH consists of ten neuropsychiatric symptoms (delusions, hallucinations, agitation/ aggression, depression, anxiety, euphoria/elation, apathy/ indifference, disinhibition, irritability/lability, aberrant motor behavior) and two neurovegetative symptoms (nighttime behavior disturbances and appetite/eating disturbances).…”

Section: Outcome Measuresmentioning

confidence: 99%

Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia

Appelhof

Bakker

IJssel

et al. 2018

Aging & Mental Health

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Objective: The aims of the current study are (1) to explore the differences in neuropsychiatric symptoms (NPS) between young-onset dementia (YOD) and late-onset dementia (LOD), and (2) to investigate whether the possible differences can be attributed to differences in dementia subtype, gender, psychotropic drug use (PDU), or dementia severity. Method: Three hundred and eighty-six nursing home (NH) residents with YOD and 350 with LOD were included. Multilevel modeling was used to compare NPS between the groups . Furthermore, dementia subtype, gender, PDU, and dementia severity were added to the crude multilevel models to investigate whether the possible differences in NPS could be attributed to these characteristics. Results: Higher levels of apathy were found in NH residents with YOD. After the characteristics were added to the models, also lower levels of verbally agitated behaviors were found in YOD . Conclusion: We recommend that special attention be paid to interventions targeting apathy in YOD. Although no differences in other NPS were found, the PDU rates were higher in YOD, suggesting that the threshold for the use of PDU in the management of NPS is lower. This underscores the need for appropriate attention to non-pharmacological interventions for the management of NPS in YOD.

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Section: Outcome Measuresmentioning

confidence: 99%

Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia

Appelhof

Bakker

IJssel

et al. 2018

Aging & Mental Health

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“…18 The Neuropsychiatric Inventory-Questionnaire (NPI-Q) was designed to expand the applicability of the NPI to routine clinical settings. 17 Another version was designed specifically for nursing home use. The NPI-Q was crossvalidated with the NPI in 60 Alzheimer's patients.…”

Section: Resultsmentioning

confidence: 99%

“…The NPI-Q was crossvalidated with the NPI in 60 Alzheimer's patients. 17 The NPI-Q is a brief, informant-based, 2-page, selfadministered assessment of neuropsychiatric symptoms and associated caregiver distress (see Appendix 1). Written instructions are provided to the caregiver who then uses anchor points to rate symptom severity and caregiver distress.…”

Section: Resultsmentioning

confidence: 99%

Measures to Assess the Noncognitive Symptoms of Dementia in the Primary Care Setting

Forester

Oxman

2003

Prim. Care Companion CNS Disord.

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“…The NPI and NPI-Q measure twelve behavioral domains including depression, apathy, irritability, agitation, anxiety, disinhibition, delusions, aberrant motor behavior, euphoria, hallucinations, night-time behaviors, and appetite/eating change. Both NPI and NPI-Q have been shown to be reliable and valid scales 17, 18 .…”

Section: Methodsmentioning

confidence: 99%

Neuropsychiatric Aspects of Primary Progressive Aphasia

Fatemi¹,

Boeve²,

Duffy³

et al. 2011

Journal of Neuropsychiatry

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Few studies have reported neuropsychiatric symptoms (NPS) in Primary Progressive Aphasia (PPA), a neurodegenerative disorder that primarily affects the left hemisphere. Depression is associated with left-sided stroke, but it remains unclear if depression and other NPS are also associated with PPA. The authors compared the frequency of NPS in 55 cases of PPA with 110 cognitively normal persons matched for age, sex and education. Depression, apathy, agitation, anxiety, appetite change, and irritability are associated with PPA. Hallucinations, delusion and night time behavior were not associated with PPA.

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Validation of the NPI-Q, a Brief Clinical Form of the Neuropsychiatric Inventory

Cited by 1,447 publications

References 24 publications

Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia

Differences in neuropsychiatric symptoms between nursing home residents with young-onset dementia and late-onset dementia

Measures to Assess the Noncognitive Symptoms of Dementia in the Primary Care Setting

Neuropsychiatric Aspects of Primary Progressive Aphasia

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