Validation of the Nottingham Hip Fracture Score (NHFS) to predict 30-day mortality in patients with an intracapsular hip fracture

Jong, Louis de; Klem, T.M.A.L.; Kuijper, M.; Roukema, Gert R.

doi:10.1016/j.otsr.2019.02.004

Cited by 26 publications

(31 citation statements)

References 27 publications

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“…20,21 Hip fractures substantially increase the risk of death and major morbidity in the elderly. 22,23 Meta-analysis demonstrated that COVID-19 was associated with increased risk of mortality in patients with hip fracture. Worldwide, the mortality rate of patients with COVID-19 is mostly around 3e4%, and mortality in the pooled analysis of hip fracture patients without COVID-19 is 4%, both are markedly lower than the 36% found for patients with hip fracture and concomitant COVID-19.…”

Section: Discussionmentioning

confidence: 99%

“…45 Various risk stratification tools that mortality and morbidity risk of patients have been developed to predict 30-day mortality risk after surgery, with the Nottingham Hip Fracture Score (NFHS) having reasonable discrimination and providing the most promising results. 23 Hip surgery can contribute to the patient's overall stability, enhanced physiological ventilation, seated mobilization, and general comfort in bed. 46 It has been found that the reduced time to surgery (within 24 h of emergency room admission) in elderly patients with hip fracture significantly decreases 1-year mortality and morbidity.…”

Section: Discussionmentioning

confidence: 99%

“… 20 , 21 Hip fractures substantially increase the risk of death and major morbidity in the elderly. 22 , 23 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

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Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture – A systematic review and meta-analysis

Lim

Pranata

2021

Journal of Clinical Orthopaedics and Trauma

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Introduction: This systematic review and meta-analysis aimed to evaluate the prevalence of coronavirus disease 2019 (COVID-19) and its impact on mortality in patients with hip fracture. Methods: We performed a systematic literature search in PubMed, Cochrane Central Database, and medRvix from inception up to July 13, 2020 on research articles that enrolled hip fracture patients who had information on COVID-19 and clinically validated definition of death. Results: A total of 984 participants from 6 studies were included in our study. The pooled prevalence of COVID-19 was 9% [95% CI: 7e11%]. The mortality rate in patients with concomitant hip fracture and COVID-19 was found to be 36% (95% CI: 26e47%), whereas the mortality rate in hip fracture without COVID-19 is 2% (95% CI: 1e3%). Meta-analysis showed that COVID-19 was associated with a seven-fold increase in risk (RR 7.45 [95% CI: 2.72, 20.43], p < 0.001; I 2 : 68.6%) of mortality in patients with hip fracture. Regression-based Harbord's test showed no indication of small-study effects (p ¼ 0.06). Conclusion: The present meta-analysis showed that COVID-19 increased the risk of mortality in patients with hip fracture.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

“… 20 , 21 Hip fractures substantially increase the risk of death and major morbidity in the elderly. 22 , 23 …”

Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

See 2 more Smart Citations

Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture – A systematic review and meta-analysis

Lim

Pranata

2021

Journal of Clinical Orthopaedics and Trauma

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“…16 Findings suggest that for a patient with a hemiarthroplasty following an intracapsular hip fracture, there could be an underestimation for the 30-day mortality rate following the NHFS prediction model. 16 In our prospective database the NHFS will be calculated and used as a benchmark model for prediction of 30-day mortality.…”

Section: Mortality Prediction Toolsmentioning

confidence: 87%

Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient

et al. 2020

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IntroductionThe primary aim is to validate earlier suggested risk factors and to find new associated risk factors for (30-day) mortality after a hip fracture in the frail population. The secondary aim is to determine the factors associated with perioperative complications. At last we want to develop and validate a more specific 30-day mortality prediction tool compared with the Nottingham Hip Fracture Score. The 30-day mortality prediction can help inform surgical risk and guide shared decision-making among patients, family and physicians.Methods and analysisThe study is designed as a prospective multicentre cohort study within the area of Rotterdam, the Netherlands starting from January 2018. All patients over 65 years of age, with an acute proximal hip fracture, are included. Treatment of patients will be by standard practice of care using the latest national and international guidelines. Inclusion will be continued at least until January 2021 and including at least 2500 patients. In this large cohort we hope to have sufficient strength and quality to identify risk factors of 30-day mortality and to compare them to known risk factors in literature. Moreover, we plan to develop and validate a 30-day mortality prediction tool, which identifies patients with a high probability of 30-day mortality.Ethics and disseminationEthical approval for this protocol was given by the Ethics Committee of the Maasstad Hospital (TWOR). Patient data are stored anonymously using the Castor data management system. No external funding is used for this study. Results will be published in peer-reviewed publications and at international conferences.Trial registration numberNL8313.

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Performance of the Nottingham Hip Fracture Score and Clinical Frailty Scale as predictors of short and long-term outcomes: a dual-centre 3-year observational study of hip fracture patients

Thorne¹,

Hodgson

2021

J Bone Miner Metab

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Validation of the Nottingham Hip Fracture Score (NHFS) to predict 30-day mortality in patients with an intracapsular hip fracture

Cited by 26 publications

References 27 publications

Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture – A systematic review and meta-analysis

Coronavirus disease 2019 (COVID-19) markedly increased mortality in patients with hip fracture – A systematic review and meta-analysis

Prospective cohort protocol examining the perioperative indicators for complications and early mortality following hip fracture surgery in the frail patient

Performance of the Nottingham Hip Fracture Score and Clinical Frailty Scale as predictors of short and long-term outcomes: a dual-centre 3-year observational study of hip fracture patients

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