Validation of the isovolumetric relaxation time for the estimation of pulmonary systolic arterial blood pressure in chronic pulmonary hypertension

Cabrita, Inês Zimbarra; Ruisánchez, Cristina; Grapsa, Julia; Dawson, David M.; North, Bernard; Pinto, Fausto J.; Gibbs, J. Simon R.; Nihoyannopoulos, Petros

doi:10.1093/ehjci/jes093

Cited by 25 publications

(16 citation statements)

References 32 publications

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“…TDI is superior to the blood flow Doppler, since it reflects the functional status of the myocardium directly, and is less subject to background noise and the loading condition (10). In several studies, the correlations between the RV IVRT from the TDI variables of the lateral tricuspid annulus and PAP have been evaluated (3,(7)(8)(9)(10)(11)(12)(13). The RV IVRT, that is, the time interval between the pulmonary valve closure (PVc) and tricuspid valve opening (TVo), has correlated well with the invasively measured SPAP in some previous studies (7)(8)(9).…”

Section: Discussionmentioning

confidence: 99%

Time from the beginning of the right ventricle isovolumetric contraction to the peak of the S wave: A new TDI indicator for the non-invasive estimation of pulmonary hypertension

et al. 2016

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Section: Discussionmentioning

confidence: 99%

Time from the beginning of the right ventricle isovolumetric contraction to the peak of the S wave: A new TDI indicator for the non-invasive estimation of pulmonary hypertension

et al. 2016

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“… BSA: body surface area; HFrEF: left heart failure with reduced ejection fraction; IVRT: isovolumic relaxation time; LV: left ventricle; PA: pulmonary artery; PAH: pulmonary arterial hypertension; PET: positron emission tomography; PH: pulmonary hypertension; RA: right atrium; RV: right ventricle; RVEF: RV ejection fraction; RVFAC: RV fractional area change; RVMPI: RV myocardial performance index; SPECT: single photon emission computed tomography; TAPSE: tricuspid annular plane systolic excursion; TDI: tissue Doppler imaging. * Normative values and thresholds are from the following references: (8–14). …”

Section: Figurementioning

confidence: 99%

Right heart imaging in patients with heart failure

Amsallem

Kuznetsova

Hanneman

et al. 2016

Current Opinion in Cardiology

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Purpose of review To describe the recent advances made in imaging of the right heart, including deformation imaging, tissue and flow characterization by resonance imaging (MRI), and molecular imaging. Recent findings Recent developments have been made in the field of deformation imaging of the right heart, which may improve risk stratification of patients with heart failure and pulmonary hypertension. In addition, more attention has been given to load adaptability metrics of the right heart; these simplified indices however still face challenges from a conceptual point of view. The emergence of novel MRI sequences, such as native T1 mapping, allows better detection and quantification of myocardial fibrosis and could allow better prediction of post-surgical recovery of the right heart. Other advances in MRI include four-dimensional flow imaging, which may be particularly useful in congenital heart disease or for the detection of early stages of pulmonary vascular disease. Summary This review will place the recent developments in right heart imaging in the context of clinical care and research.

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“…This in turn causes the RV to become more spherical in structure and impairs LV function. The clinical assessment of RV diastolic dysfunction can be performed (1) non-invasively using imaging techniques such as echocardiography [5,25] and cardiac magnetic resonance (CMR) [26,27] and (2) invasively using right heart catheterisation (RHC) [28], conductance catheterisation [29,30] and radionuclide angiography [31].…”

Section: Non-invasive and Invasive Assessment Of Rv Diastolic Dysfuncmentioning

confidence: 99%

“…This is the time interval between the closure of the pulmonary valve and the opening of the tricuspid valve. An RV IVRT [75 ms is considered to be abnormal [25]. RV IVRT has been shown to correlate well with pulmonary arterial systolic pressure [25].…”

Section: Echocardiographymentioning

confidence: 99%

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RV diastolic dysfunction: time to re-evaluate its importance in heart failure

et al. 2015

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Right ventricular (RV) diastolic dysfunction was first reported as an indicator for the assessment of ventricular dysfunction in heart failure a little over two decades ago. However, the underlying mechanisms and precise role of RV diastolic dysfunction in heart failure remain poorly described. Complexities in the structure and function of the RV make the detailed assessment of the contractile performance challenging when compared to its left ventricular (LV) counterpart. LV dysfunction is known to directly affect patient outcome in heart failure. As such, the focus has therefore been on LV function. Nevertheless, a strategy for the diagnosis and assessment of RV diastolic dysfunction has not been established. Here, we review the different causal mechanisms underlying RV diastolic dysfunction, summarising the current assessment techniques used in a clinical environment. Finally, we explore the role of load-independent indices of RV contractility, derived from the conductance technique, to fully interrogate the RV and expand our knowledge and understanding of RV diastolic dysfunction. Accurate assessment of RV contractility may yield further important prognostic information that will benefit patients with diastolic heart failure.

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Validation of the isovolumetric relaxation time for the estimation of pulmonary systolic arterial blood pressure in chronic pulmonary hypertension

Abstract: The determination of IVRT by DTI is a simple and reproducible method that correlates well with PASP. It is, therefore, a parameter to consider in the echocardiographic assessment of patients with PH, and may be particularly important when the tricuspid Doppler signal is poor.

Cited by 25 publications

References 32 publications

Time from the beginning of the right ventricle isovolumetric contraction to the peak of the S wave: A new TDI indicator for the non-invasive estimation of pulmonary hypertension

Time from the beginning of the right ventricle isovolumetric contraction to the peak of the S wave: A new TDI indicator for the non-invasive estimation of pulmonary hypertension

Right heart imaging in patients with heart failure

RV diastolic dysfunction: time to re-evaluate its importance in heart failure

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