Validation of the Hip Disability and Osteoarthritis Outcome Score and Knee Injury and Osteoarthritis Outcome Score Pain and Function Subscales for Use in Total Hip Replacement and Total Knee Replacement Clinical Trials

Goodman, Susan M.; Mehta, Bella; Mandl, Lisa A.; Szymonifka, Jackie; Finik, Jackie; Figgie, Mark P.; Navarro‐Millán, Iris; Bostrom, Mathias P.; Parks, Michael L.; Padgett, Douglas E.; McLawhorn, Alexander S.; Antao, Vinicius C.; Yates, Adolph J.; Springer, Bryan D.; Lyman, Stephen; Singh, Jasvinder A

doi:10.1016/j.arth.2019.12.038

Cited by 34 publications

(29 citation statements)

References 34 publications

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“…Nevertheless, it is associated with large local wounds and a prolonged healing process due to a volume of blood transfusion after surgery, thereby increasing the risk of deep vein thromboembolism and seriously compromising the prognosis of patients. Some scholars have found that the application of tranexamic acid to patients undergoing TKA can effectively reduce postoperative bleeding and reduce the risk of postoperative complications [7][8][9]. With this background, the present study was conducted to further explore the effect of oral tranexamic acid treatment on the blood transfusion rate and the incidence of deep vein thromboembolism in patients after TKA.…”

Section: Introductionmentioning

confidence: 98%

Effect of Oral Tranexamic Acid on the Blood Transfusion Rate and the Incidence of Deep Vein Thromboembolism in Patients after TKA

Chen

Fang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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Purpose. To explore the effect of oral tranexamic acid treatment on the blood transfusion rate and the incidence of deep vein thromboembolism after total knee arthroplasty (TKA). Methods. 90 patients undergoing TKA admitted to First People’s Hospital of Changshu City from January 2019 to January 2020 were selected and randomized into the control group and the experimental group accordingly (45 cases in each group). The control group intravenously received 20 mL/kg tranexamic acid before the incision was closed. The experimental group was given 1 g of tranexamic acid orally before anesthesia, 6 h and 12 h after the operation. Results. The experimental group witnessed better perioperative indexes in relation to the control group. The experimental group displayed better postoperative coagulation function indexes as compared to the control group ( P < 0.05 ). Remarkably lower postoperative vascular endothelial function indexes in the experimental group than in the control group were observed. The experimental group experienced a markedly lower incidence of deep vein thromboembolism in comparison with the control group ( P < 0.05 ). The postoperative knee society score (KSS) score of the experimental group was significantly higher than that of the control group. A significantly higher postoperative modified rivermead mobility index (MRMI) score was yielded in the experimental group in contrast to the control group ( P < 0.05 ). The experimental group obtained lower numerical rating scale (NRS) scores at T2 and T3 as compared to the control group. Conclusion. Oral tranexamic acid is a suitable alternative for patients undergoing TKA in terms of reducing the blood transfusion rate, relieving pain, and accelerating the recovery of the patient’s limbs.

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Section: Introductionmentioning

confidence: 98%

Effect of Oral Tranexamic Acid on the Blood Transfusion Rate and the Incidence of Deep Vein Thromboembolism in Patients after TKA

Chen

Fang

et al. 2022

Evidence-Based Complementary and Alternative Medicine

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“…Developed specifically for TJA, the Knee injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS JR) and the Hip disability and Osteoarthritis Outcome Score, Joint Replacement (HOOS JR) are 2 commonly administered PROMs for which the MCID and the substantial clinical benefit (SCB) have been defined [17][18][19] . However, the PASS for these PROMs in TJA has not yet been established.…”

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confidence: 99%

Defining the Patient Acceptable Symptom State for the HOOS JR and KOOS JR After Primary Total Joint Arthroplasty

Kunze

Fontana

MacLean

et al. 2021

Journal of Bone and Joint Surgery

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Background: It is essential to quantify an acceptable outcome after total joint arthroplasty (TJA) in order to understand quality of care. The purpose of this study was to define patient acceptable symptom state (PASS) thresholds for the Knee injury and Osteoarthritis Outcome Score, Joint Replacement (KOOS JR) and the Hip disability and Osteoarthritis Outcome Score, Joint Replacement (HOOS JR) after TJA.Methods: A receiver operating characteristic (ROC) curve analysis, leveraging 2-year satisfaction of "moderate improvement" or better as the anchor, was used to establish PASS thresholds among 5,216 patients who underwent primary total hip arthroplasty and 4,036 who underwent primary total knee arthroplasty from 2007 to 2012 with use of an institutional registry. Changes in PASS thresholds were explored by stratifying and recalculating these thresholds by age at the time of surgery (<70 or ‡70 years of age), sex (men or women), body mass index (BMI; <30 or ‡30 kg/m 2 ), and baseline Short Form-36 (SF-36) physical and mental component scores (<50 or ‡50). Results:The HOOS JR PASS threshold was 76.7 (area under the ROC curve [AUC] = 0.91), which was achieved by 4,334 patients (83.1%). The KOOS JR PASS threshold was 63.7 (AUC = 0.89), which was achieved by 3,461 patients (85.8%). Covariate stratification demonstrated that PASS thresholds were higher in men compared with women, and in those with higher preoperative SF-36 physical and mental scores ( ‡50) compared with lower SF-36 scores (<50). Results differed between instruments for BMI and age: higher BMI was associated with a lower PASS threshold for the HOOS JR but a higher PASS threshold for the KOOS JR. The HOOS JR PASS threshold was higher in patients who were <70 years of age compared with those who were ‡70 years of age, but was equivalent for the KOOS JR. Conclusions:The PASS thresholds for the HOOS JR and KOOS JR at 2 years after TJA were 76.7 and 63.7, respectively.The PASS thresholds were associated with certain preoperative covariates, suggesting that an acceptable symptom state after TJA is influenced by patient-specific factors.

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“…[24][25][26] However, none of these studies have utilized preoperative reporting of orthopaedic outcome scores for estimating the risk of ICU admission in the setting of THA and TKA. Goodman et al 27 reported that the improved Hip Disability and Osteoarthritis Outcome Score (HOOS)/KOOS subscale scores for pain and activities of daily living (ADL) correlated with positive changes in QOL 2 years following TJA. While this information provides insight into long-term trends following arthroplasty, it does not inform about the relationship of these measures with immediate postoperative outcomes.…”

Section: Discussionmentioning

confidence: 99%

Can We Predict Unplanned Intensive Care Unit Admission in Hip and Knee Arthroplasty?

Sinclair

Briskin

Klika

et al. 2021

The Journal of Hip Surgery

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Preoperative risk stratification remains important for both patient safety and cost-effective allocation of resources in total joint arthroplasty. Limited literature exists investigating risk factors for unplanned intensive care unit (ICU) admission following arthroplasty. Therefore, the purpose of this study was to assess a broader spectrum of factors that may increase the risk of ICU admission across multiple surgical settings. We retrospectively reviewed 18,169 patients who underwent a hip (40.7%) or knee (59.3%) arthroplasty procedure (primary: n = 13,384, 90%; revision: n = 1,485, 10%) between August 1, 2015, and January 31, 2019, across nine sites at a single institution. Patient demographics, laboratory data, surgical parameters, and preoperative scores on the Hip Disability and Osteoarthritis Outcome Score (HOOS) or Knee Injury and Osteoarthritis Outcome Score (KOOS) and the Veterans RAND 12-Item Health Survey (VR-12) were recorded. A univariate analysis was conducted to identify differences between patients who required an ICU admission and those with no ICU involvement. Logistic regression was then used to generate predicted risk of ICU Involvement. A total of 147 patients (0.99%) required an ICU admission. Increasing age, higher Charlson's comorbidity index, American Society of Anesthesiologists (ASA) class 3 or greater, elevated blood urea nitrogen (BUN), elevated creatinine, decreased preoperative hemoglobin level, general anesthesia, surgical setting, revision procedure, and lower baseline scores on the KOOS Quality of Life (QOL) subscale (17 vs. 22.5, p = 0.032), VR-12 physical component score (PCS; 24.4 vs 27.1, p = 0.001), and VR-12 mental component score (MCS; 45.9 vs. 49.6, p = 0.003) were associated with a statistically significant increase in the risk of ICU admission. As performance of arthroplasty shifts in both the setting of care and the complexity of patients, identifying patients most at risk of requiring higher acuity of care is important. Preoperative assessment of comorbidities, kidney function, surgical setting, KOOS QOL subscale score, and VR-12 scores may provide guidance for the improvement of value-based care pathways.

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Validation of the Hip Disability and Osteoarthritis Outcome Score and Knee Injury and Osteoarthritis Outcome Score Pain and Function Subscales for Use in Total Hip Replacement and Total Knee Replacement Clinical Trials

Cited by 34 publications

References 34 publications

Effect of Oral Tranexamic Acid on the Blood Transfusion Rate and the Incidence of Deep Vein Thromboembolism in Patients after TKA

Effect of Oral Tranexamic Acid on the Blood Transfusion Rate and the Incidence of Deep Vein Thromboembolism in Patients after TKA

Defining the Patient Acceptable Symptom State for the HOOS JR and KOOS JR After Primary Total Joint Arthroplasty

Can We Predict Unplanned Intensive Care Unit Admission in Hip and Knee Arthroplasty?

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