Validation of the Gross Motor Function Measure for Use in Children and Adolescents With Traumatic Brain Injuries

Linder-Lucht, M; Othmer, Verena; Walther, Michael; Vry, Julia; Michaelis, U.; Stein, Sabine; Weissenmayer, H; Korinthenberg, Rudolf; Mall, Volker

doi:10.1542/peds.2006-2258

Cited by 64 publications

(45 citation statements)

References 24 publications

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“…The GMFM-66 is derived from the GMFM-88 using Rasch analysis. Responsiveness to change in motor function using the GMFM-88 after pediatric TBI has been demonstrated in multiple studies (Kuhtz-Buschbeck et al, 2003;Linder-Lucht et al, 2007;Thomas-Stonell et al, 2006) and the GMFM-66 as well as the GMFM-88 have recently demonstrated sensitivity and discriminant validity, with excellent test-retest reliability, for use in children and adolescents with TBI (Linder-Lucht et al, 2007). The GMFM was validated with children and adolescents from 5 months to 16 years of age and is appropriate for children with motor skills at or below those of a 5-year-old child without motor disability.…”

Section: Physical Functioningmentioning

confidence: 99%

Recommendations for the Use of Common Outcome Measures in Pediatric Traumatic Brain Injury Research

McCauley

Wilde

Anderson

et al. 2012

Journal of Neurotrauma

282

207

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This article addresses the need for age-relevant outcome measures for traumatic brain injury (TBI) research and summarizes the recommendations by the inter-agency Pediatric TBI Outcomes Workgroup. The Pediatric Workgroup's recommendations address primary clinical research objectives including characterizing course of recovery from TBI, prediction of later outcome, measurement of treatment effects, and comparison of outcomes across studies. Consistent with other Common Data Elements (CDE) Workgroups, the Pediatric TBI Outcomes Workgroup adopted the standard three-tier system in its selection of measures. In the first tier, core measures included valid, robust, and widely applicable outcome measures with proven utility in pediatric TBI from each identified domain including academics, adaptive and daily living skills, family and environment, global outcome, health-related quality of life, infant and toddler measures, language and communication, neuropsychological impairment, physical functioning, psychiatric and psychological functioning, recovery of consciousness, social role participation and social competence, social cognition, and TBI-related symptoms. In the second tier, supplemental measures were recommended for consideration in TBI research focusing on specific topics or populations. In the third tier, emerging measures included important instruments currently under development, in the process of validation, or nearing the point of published findings that have significant potential to be superior to measures in the core and supplemental lists and may eventually replace them as evidence for their utility emerges.

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Section: Physical Functioningmentioning

confidence: 99%

Recommendations for the Use of Common Outcome Measures in Pediatric Traumatic Brain Injury Research

McCauley

Wilde

Anderson

et al. 2012

Journal of Neurotrauma

282

207

View full text Add to dashboard Cite

show abstract

“…More sensitive, domain-specific instruments that have been validated for use in pediatric acquired brain injuries include measures of gross motor function, 21 functional independence, 22,23 health-related quality of life 24 and neuropsychological function. 25 Recent consensus statements 26 have suggested standardized "core data elements" that should be captured by all rehabilitation re searchers to allow the comparison and aggregation of rehabilitation outcomes.…”

Section: What Factors Determine Outcome After Acquired Brain Injury?mentioning

confidence: 99%

Predicting outcome after childhood brain injury: Figure 1:

Forsyth¹,

Kirkham²

2012

CMAJ

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“…13,17 Motor deficits are an important characteristic of pediatric TBI and an indicator of recovery. Many motor function scales are currently used in children (Gross Motor Function Measure, Peabody Development Scales, Bruininks-Oseretsky Test of Motor Proficiency, Functional Reach Test), 7,8,[31][32][33] making the use of a motor proficiency scale in piglets an appropriate translational tool.…”

Section: Discussionmentioning

confidence: 99%

Improved Behavior, Motor, and Cognition Assessments in Neonatal Piglets

Sullivan

Friess

Ralston

et al. 2013

Journal of Neurotrauma

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The alterations of animal behavior after traumatic brain injury (TBI) can be subtle, and their quantitative characterization can present significant methodological challenges. Meeting these challenges is a critical need, because quantitative measures are required in studies that compare the efficacy of different clinical interventions. We developed a battery of assessments to quantify behavioral, motor, and cognitive changes in neonatal piglets with good sensitivity and specificity to the detection of persistent deficits that correlate with axonal injury severity after a rapid non-impact head rotation with a diffuse pattern of axonal injury. The battery of measures developed included open field behaviors of sniffing and moving a toy, locomotion measures of Lempel-Ziv complexity and the probability of remaining in the current location, and a novel metric for evaluating motor performance. Our composite porcine disability score was able to detect brain injury with a sensitivity of 100% and specificity of 85.7% at day + 4 post-injury for n = 8 injured and n = 7 sham piglets and significantly correlated with the percent axonal injury in these animals (day + 4: q = 0.76, p = 0.0011). A significant improvement over our previous assessments, this new porcine disability score has potential use in a wide variety of porcine disease and injury models.

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Validation of the Gross Motor Function Measure for Use in Children and Adolescents With Traumatic Brain Injuries

Abstract: We demonstrate convincing evidence of responsiveness and validity to support the use of both Gross Motor Function Measure versions as evaluative measures of gross motor function in children and adolescents with traumatic brain injury.

Cited by 64 publications

References 24 publications

Recommendations for the Use of Common Outcome Measures in Pediatric Traumatic Brain Injury Research

Recommendations for the Use of Common Outcome Measures in Pediatric Traumatic Brain Injury Research

Predicting outcome after childhood brain injury: Figure 1:

Improved Behavior, Motor, and Cognition Assessments in Neonatal Piglets

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