Validation of the French version of the Leicester Cough Questionnaire in chronic obstructive pulmonary disease

Abstract

Cough is one of the three major symptoms reported by chronic obstructive pulmonary disease (COPD) patients. The Leicester Cough Questionnaire (LCQ) is a questionnaire exploring the impact of cough, but it does not exist in French. The aim of this study was to develop a French version of LCQ and to assess its psychometrics properties. A forward-backward translation process was used to develop the French version of the LCQ. COPD patients completed LCQ and Cough and Sputum Assessment Questionnaire (CASA-Q) to determine concurrent validity, content validity and internal consistency. Two weeks later, the LCQ was repeated to evaluate the reproducibility. Seventy-four COPD patients were recruited. The concurrent validity showed highly significant correlations between all scores of LCQ and CASA-Q (p < 0.001). The content validity was good with domain total scores correlations ranging from 0.918 to 0.953. The LCQ domains and total scores showed a very good internal consistency with Cronbach's a coefficients ranging between 0.802 and 0.917. The test-retest reliability was high in COPD patients with no change in cough. In conclusion, The French version of the LCQ is a valid and reliable instrument to measure health status in COPD patients.

<p>Minimal Clinically Important Differences for Patient-Reported Outcome Measures of Cough and Sputum in Patients with COPD</p>

“…This may explain the observed ceilings effects and why impact of cough and sputum in the HRQoL of our participants was comparable to other studies enrolling patients with COPD, 31,56 but different (our sample scored better) from studies considering patients with chronic cough only. 28,57,58 Although previous research has showed a relationship between CAT and cough and sputum, 59,60 in our study an association was verified only with cough. However, association was explored with mean changes, while previous studies have focused on absolute scores.…”

Validation of a Spanish version of the Leicester Cough Questionnaire in non-cystic fibrosis bronchiectasis

“…12,16 The LCQ has been also validated in other languages in chronic cough [33][34][35] and in COPD. 36,37 The results in repeatability and concurrent validity measured with different questionnaires are similar to our results. [33][34][35][36][37] Responsiveness has been studied at 2 or 6 months after improvement or treatment but not at the beginning of an exacerbation.…”

“…36,37 The results in repeatability and concurrent validity measured with different questionnaires are similar to our results. [33][34][35][36][37] Responsiveness has been studied at 2 or 6 months after improvement or treatment but not at the beginning of an exacerbation. No data about feasibility, discriminant validity were reported.…”

The validity and reliability of the Turkish version of the Leicester Cough Questionnaire in COPD patients

“…In the Turkish validity study of the LCQ in patients with chronic cough, the relationship between LCQ subscales and SF-36 subscales was found to be significant, in parallel with our study (5). Kwon (25). The study of Birring et al also showed that the LCQ is suitable for use in many areas.…”

“…Sönnerfors et al also showed that the questionnaire correlated with the Swedish version of the LCQ with the St George's Respiratory Questionnaire and the COPD Assessment Test, and indicated that the questionnaire could be used (24). Reychler et al also tested the French version of the questionnaire with the Cough and Sputum Assessment Questionnaire and found a strong correlation (25). The study of Birring et al also showed that the LCQ is suitable for use in many areas.…”