Validation of the Cumulative Illness Rating Scale in a Geriatric Residential Population

Parmelee, Patricia A.; Thuras, Paul; Katz, Ira R.; Lawton, M. Powell

doi:10.1111/j.1532-5415.1995.tb06377.x

Cited by 833 publications

(524 citation statements)

References 32 publications

(27 reference statements)

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“…Medical comorbidity was measured with the total score from the Cumulative Illness Rating Scale (CIRS), which combines the presence and severity of common medical comorbidities (Parmelee et al, 1995). BMI was assessed as a measure of body fat based on height and weight that applies to adult women and men (kg/m 2 ).…”

Section: Medical Comorbiditymentioning

confidence: 99%

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Wolkowitz

Jeste

Martin

et al. 2017

Journal of Psychiatric Research

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a b s t r a c tBackground: Schizophrenia is linked with early medical comorbidity and mortality. These observations indicate possible "accelerated biological aging" in schizophrenia, although prior findings are mixed, and few such studies have examined the role of gender. One putative marker of biological aging is leukocyte telomere length (LTL), which typically shortens with age. Methods: We assessed LTL in phenotypically well characterized 134 individuals with schizophrenia (60 women and 74 men) and 123 healthy comparison subjects (HCs) (66 women and 57 men), aged 26 to 65 years. Results: Overall, LTL was inversely associated with age (t(249) ¼ -6.2, p < 0.001), and a gender effect on the rate of LTL decrease with age was found (t(249) ¼ 2.20, p ¼ 0.029), with men declining more rapidly than women. No significant overall effect of diagnosis on the rate of decline was detected. However, at the average sample age (48 years), there was a significant gender effect in both schizophrenia and HC groups (t(249) ¼ 2.48, p ¼ 0.014), with women having longer LTL than men, and a significant gender X diagnosis effect (t(249) ¼ 2.43, p ¼ 0.016) -at the average sample age, women with schizophrenia had shorter LTL than HC women. Discussion: Gender, not the diagnosis of schizophrenia, was the major factor involved with LTL shortening across the age range studied. We discuss the constraints of a cross-sectional design and other methodological issues, and indicate future directions. Understanding the impact of schizophrenia on biological aging will require separate evaluations in men and women.Published by Elsevier Ltd.

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Section: Medical Comorbiditymentioning

confidence: 99%

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Wolkowitz

Jeste

Martin

et al. 2017

Journal of Psychiatric Research

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“…All subjects underwent a comprehensive geriatric evaluation: functional status was assessed by means of the scales for the Activities of Daily Living (ADL) (Katz et al 1970) and the Instrumental Activities of Daily Living (IADL) (Lawton and Brody 1969), balance and gait abilities by means of the Performance-Oriented Mobility Assessment (POMA) (Tinetti 1986), cognitive status by means of the Mini Mental State Examination (MMSE) (Folstein et al 1975), emotional status by means of the 30-item Geriatric Depression Scale (GDS) (Yesavage et al 1983), morbidity by means of the Cumulative Illness Rating Scales (CIRS-m and CIRS-s) (Parmelee et al 1995).…”

Section: Design and Measurement Instrumentsmentioning

confidence: 99%

Day care centre attendance and quality of life in depressed older adults living in the community

et al. 2010

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Late-life depression is associated with disabled functioning and a poor quality of life (QOL). The aim of this cross-sectional study was to find out whether the attendance of a day care centre (DC) was associated with QOL in community-dwelling older adults suffering from a depressive disorder without dementia. The study enrolled 149 depressed older adults aged 70 or older, who consecutively underwent a comprehensive geriatric assessment from April to July 2008 at the Geriatric Medicine Unit of the Fondazione Ospedale Maggiore Policlinico in Milan, Italy. QOL was evaluated by means of the European Quality of Life Visual Analogue Scale (EuroQol VAS). DC attendance was quantified as number of days of attendance per week in the past month. Participants attending a DC at least once a week (n = 17) had a higher mean EuroQol VAS score than non-attendants (n = 132) (mean ± SD 58.8 ± 19 vs. 45.3 ± 22.5; P = 0.019). In multiple linear regression analysis a higher weekly attendance of DCs was related to a better quality of life according to the EuroQol VAS score (unstandardized coefficient 3.048, 95% CI 0.063-6.033, P = 0.045) after correction for age, sex, balance and gait abilities, comorbidity, pharmacotherapy, living alone, and severity of depression. Therefore, in older outpatients suffering from a depressive disorder without dementia the attendance of a DC was an independent correlate of the QOL. A randomized controlled longitudinal study will be necessary to determine whether attending a DC is really effective on the QOL in the management of late-life depression.

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“…They had a mean age of 86.18 ( SD = 7.89 years) and were mostly women (88.2%, n = 15) and Caucasian (82.4%, n = 14). This was a particularly frail population, with a mean baseline Cumulative Illness Rating Scale (Parmelee, Thuras, Katz, & Lawton, 1995) score of 24.82 ( SD = 3.97). The mean baseline MMSE score was 23.18 ( SD = 4.63), and the mean GDS score was 10.12 ( SD = 6.04).…”

Section: Methodsmentioning

confidence: 99%

“…Cumulative Illness Rating Scale for comorbidity and change in status (Parmelee, Thuras, Katz, & Lawton, 1995)…”

Section: Tablementioning

confidence: 99%

Disaster Strikes! Long-Term Care Resident Outcomes Following a Natural Disaster

Cacchione

Willoughby²,

Langan³

et al. 2011

J Gerontol Nurs

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This report describes the outcomes of 17 long-term care residents who were participating in a nursing intervention study. The residents were evacuated for 5 days due to a severe summer storm that caused widespread power outages. These residents were seen the day of the storm and three times per week for 2 weeks following their return to the nursing home. More than half of the participants had significant changes in their NEECHAM Confusion Scale scores (n = 11) and modified Confusion Assessment Method scores (n = 9) scores, suggesting the onset of delirium. Two participants were hospitalized within the 2 weeks of the evacuation. One participant died unexpectedly. This report provides a rare look into the negative effects of a short-term evacuation due to a natural disaster.

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Validation of the Cumulative Illness Rating Scale in a Geriatric Residential Population

Cited by 833 publications

References 32 publications

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Leukocyte telomere length: Effects of schizophrenia, age, and gender

Day care centre attendance and quality of life in depressed older adults living in the community

Disaster Strikes! Long-Term Care Resident Outcomes Following a Natural Disaster

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