Validation of the Chinese version of functional assessment of anorexia-cachexia therapy (FAACT) scale for measuring quality of life in cancer patients with cachexia

Zhou, Ting; Yang, Kai; Thapa, Sudip; Fu, Qiang; Jiang, Yongsheng; Yu, Shiying

doi:10.1007/s00520-016-3508-4

Cited by 13 publications

(25 citation statements)

References 38 publications

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“…Therefore, exploration of the evaluation tools of cachexia in MHD-treated patients is of high clinical signi cance. FAACT has been veri ed as a tool to measure the quality of life of patients with cachexia related to many diseases [8,9] . This study may serve as a reference for the evaluation of cachexia in MHD-treated patients and for the development of FAACT scale.…”

Section: Discussionmentioning

confidence: 99%

“…This study assessed the reliability and validity of FAACT in MHD-treated patients. In terms of reliability (Table 2), Cronbach's alpha was acceptable, but PWB and FWB were less than 0.7, and FAACT and ACS performed better than other disease detection areas [8,21] . The performance of FAACT test-retest was also outstanding, with the retest coe cients of all dimensions exceeding 0.8.…”

Section: Discussionmentioning

confidence: 99%

“…All items were rated as a ve-level scoring system: not at all, a little bit, somewhat, quite a bit, and very much. Higher FAACT scores corresponded to better quality of life, and lower ACS scores corresponded to severe cachexia [8] .…”

Section: Assessment Schedulementioning

confidence: 94%

“…FAACT is an instrument used to assess the quality of life of patients with anorexia and cachexia. This instrument includes 39 terms in ve dimensions: physical well-being (PWB; 7 items), social well-being (SWB; 7 items), emotional well-being (EWB; 6 items), functional well-being (FWB; 7 items), and anorexiacachexia subscale (ACS; 12 items) [8] . Most of the items (PWB, SWB, EWB, and FWB) were drawn from the general chronic illness questionnaire FACT-G [9,13] .…”

Section: Assessment Schedulementioning

confidence: 99%

“…However, a clinical tool to assess cachexia in MHD-treated patients is lacking. FAACT is a tool used to assess the quality of life of patients with cancer, AIDS, and some chronic diseases [8,9] . However, its availability in MHD-treated patients has not been demonstrated.…”

Section: Introductionmentioning

confidence: 99%

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Validation of the Functional Assessment of Anorexia/Cachexia Therapy Instrument to Assess Quality of Life in Maintenance Hemodialysis-Treated Patients with Cachexia

Zhang¹,

Huang²,

Ping³

et al. 2020

Preprint

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Background Cachexia is the ultimate state of many maintenance hemodialysis (MHD)-treated patients. Functional Assessment of Anorexia/Cachexia Therapy (FAACT) is a tool used to evaluate the quality of life of patients with cachexia related to various diseases, but its effectiveness in MHD-treated patients has yet to be verified. This study aims to explore the applicability of FAACT in MHD-treated patients.Methods Qualified MHD-treated patients were selected for FAACT and The Kidney Disease Quality of Life Short Form 36 (KDQOL-36) questionnaire survey, and their demographic data and biochemical test results were collected from electronic medical records. Then, data were analyzed using statistical methods.Results This study enrolled 299 effective patients. The reliability of FAACT and its anorexia-cachexia subscale (ACS) were 0.904 and 0.842, respectively, and their retest exceeded 0.85. A reasonable correlation was found between FAACT and its items, and a reasonable calibration validity was identified between FAACT and KDQOL-36 subscale. FAACT and its subscale ACS showed good discriminant validity in the comparison of patients with different cachexia states and inflammatory states.Conclusions FAACT and ACS have good reliability and validity in MHD-treated patients and are suitable to measure the quality of life of MHD-treated patients with cachexia.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Section: Assessment Schedulementioning

confidence: 94%

Section: Assessment Schedulementioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Validation of the Functional Assessment of Anorexia/Cachexia Therapy Instrument to Assess Quality of Life in Maintenance Hemodialysis-Treated Patients with Cachexia

Zhang¹,

Huang²,

Ping³

et al. 2020

Preprint

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Development and validation of a clinically applicable score to classify cachexia stages in advanced cancer patients

Zhou

Wang

Liu

et al. 2018

J cachexia sarcopenia muscle

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BackgroundCachexia is a multifactorial syndrome that is highly prevalent in advanced cancer patients and leads to progressive functional impairments. The classification of cachexia stages is essential for diagnosing and treating cachexia. However, there is a lack of simple tools with good discrimination for classifying cachexia stages. Therefore, our study aimed to develop a clinically applicable cachexia staging score (CSS) and validate its discrimination of clinical outcomes for different cachexia stages.MethodsAdvanced cancer patients were enrolled in our study. A CSS comprising the following five components was developed: weight loss, a simple questionnaire of sarcopenia (SARC‐F), Eastern Cooperative Oncology Group, appetite loss, and abnormal biochemistry. According to the CSS, patients were classified into non‐cachexia, pre‐cachexia, cachexia, and refractory cachexia stages, and clinical outcomes were compared among the four groups.ResultsOf the 297 participating patients, data from 259 patients were ultimately included. Based on the CSS, patients were classified into non‐cachexia (n = 69), pre‐cachexia (n = 68), cachexia (n = 103), and refractory cachexia (n = 19) stages. Patients with more severe cachexia stages had lower skeletal muscle indexes (P = 0.002 and P = 0.004 in male and female patients, respectively), higher prevalence of sarcopenia (P = 0.017 and P = 0.027 in male and female patients, respectively), more severe symptom burden (P < 0.001), poorer quality of life (P < 0.001 for all subscales except social well‐being), and shorter survival times (P < 0.001).ConclusionsThe CSS is a simple and clinically applicable tool with excellent discrimination for classifying cachexia stages. This score is extremely useful for the clinical treatment and prognosis of cachexia and for designing clinical trials.

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Study on the relationship between sarcopenia and its components and anorexia in elderly maintenance haemodialysis patients

Chen

et al. 2021

Nursing Open

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The global population is ageing, and the average age of patients with kidney disease is increasing. Surveys in Western countries showed that people over the age of 75 years have the highest incidence of end-stage kidney disease (Evans et al., 2018;Saran et al., 2019).After chronic kidney disease progresses to end-stage kidney disease, most patients choose to be treated with haemodialysis. The prevalence of sarcopenia in elderly patients on maintenance haemodialysis (MHD) is elevated due to the reduced muscle mass and physical activity caused by age and factors related to treatment (Lou et al., 2019). Previous studies have shown that the prevalence of sarcopenia in elderly MHD patients is 33.7%~37% (Giglio et al., 2018;Kim et al., 2014). | BackgroundSarcopenia, which is characterized by a reduction in skeletal muscle, is a progressive and widespread condition that mainly

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Validation of the Chinese version of functional assessment of anorexia-cachexia therapy (FAACT) scale for measuring quality of life in cancer patients with cachexia

Abstract: The Chinese version of FAACT scale has good reliability and validity and is suitable for measuring QOL of cachexia patients in Chinese population.

Cited by 13 publications

References 38 publications

Validation of the Functional Assessment of Anorexia/Cachexia Therapy Instrument to Assess Quality of Life in Maintenance Hemodialysis-Treated Patients with Cachexia

Validation of the Functional Assessment of Anorexia/Cachexia Therapy Instrument to Assess Quality of Life in Maintenance Hemodialysis-Treated Patients with Cachexia

Development and validation of a clinically applicable score to classify cachexia stages in advanced cancer patients

Study on the relationship between sarcopenia and its components and anorexia in elderly maintenance haemodialysis patients

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