Validation of GenProb‐T1D and its clinical utility for differentiating types of diabetes in a biobank from a US healthcare system
Liana K. Billings,
Zhuqing Shi,
Ashley J. Mulford
et al.
Abstract:Atypical diabetes with overlapping clinical features of type 1 (T1D) and type 2 (T2D) is common and challenging diagnostically and for implementing effective treatment. Here, we validate a recently reported genetic probability of type 1 diabetes (GenProb‐T1D) from the UK Biobank (UKB) for differentiating type 1 diabetes and type 2 diabetes in a diabetes patient cohort from a healthcare system‐based biobank in the USA. Among 3,363 diabetes patients, we confirmed the performance of GenProb‐T1D in differentiating… Show more
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