Validation of new medication use algorithms as proxies for worsening disease activity in patients with juvenile idiopathic arthritis
Kyoko Saito,
Avinash Gabbeta,
Evan Mulvihill
et al.
Abstract:PurposeTo facilitate claims‐based research on populations with juvenile idiopathic arthritis (JIA), we sought to validate an algorithm of new medication use as a proxy for worsening JIA disease activity.MethodsUsing electronic health record data from three pediatric centers, we defined new JIA medication use as (re)initiation of disease‐modifying antirheumatic drugs or glucocorticoids (oral or intra‐articular). Data were collected from 201 randomly selected subjects with (101) or without (100) new medication u… Show more
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