Validation of Longitudinal Peak Systolic Strain by Speckle Tracking Echocardiography With Visual Assessment and Myocardial Perfusion SPECT in Patients With Regional Asynergy

Kusunose, Kenya; Yamada, Hirotsugu; Nishio, S.; Mizuguchi, Yukio; Choraku, Masahito; Maeda, Yasuhiro; Hosokawa, Shinobu; Yamazaki, Nobuo; Tomita, Noriko; Niki, Toshiyuki; Yamaguchi, Koji; Koshiba, Kunihiko; Soeki, Takeshi; Wakatsuki, Tetsuzo; Akiyama, Masashi; Sata, Masataka

doi:10.1253/circj.cj-10-0551

Cited by 39 publications

(15 citation statements)

References 28 publications

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“…Previous studies have shown that changes of subclinical LV longitudinal systolic and diastolic function begin before structural LV changes in asymptomatic patients with HF risk factors 18, 19, 20, 21. However, comparisons of the degree of LV myocardial dysfunction in early diabetic cardiomyopathy and in other‐SAHF have not been documented previously.…”

Section: Discussionmentioning

confidence: 98%

Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies

Wang¹,

Yang²,

Nolan³

et al. 2018

ESC Heart Failure

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AimsPatients with heart failure (HF) risk factors are described as being in Stage A of this condition (SAHF). Management is directed towards prevention of HF progression, but to date, no evidence has been described to align the intensity of this intervention to HF risk. We sought to what extent SAHF of Type 2 diabetes mellitus (T2DM) and other HF risks showed differences in subclinical left ventricular function, exercise capacity, and prognosis.Methods and resultsWe recruited 551 elder asymptomatic SAHF patients (age 71 ± 5 years, 49% men, 290 T2DM) with at least one risk factor from a community‐based population with preserved ejection fraction. All underwent a comprehensive echocardiogram including global longitudinal strain (GLS) and a 6 min walk test and were followed for 2 years. The primary endpoints were new‐onset HF and all‐cause mortality. The T2DM group was associated with reduced 6 min walk test distance (451 ± 111 vs. 493 ± 87 m, P < 0.001), worse diastolic function (E/e′ 9.2 ± 2.7 vs. 8.7 ± 2.4, P = 0.028), and impaired GLS (−17.7 ± 2.6% vs. −19.0 ± 2.6%, P < 0.001). Over a median follow‐up of 1.6 years, 49 T2DM‐SAHF and 27 other‐SAHF met the primary endpoint. T2DM‐SAHF had significantly worse outcome than other‐SAHF (P = 0.021). In Cox models, obesity [hazard ratio (HR) = 2.46; P = 0.007], atrial fibrillation (HR = 2.39; P = 0.028), 6 min walk distance (HR = 0.99; P = 0.034), and GLS (HR = 1.14; P = 0.033) were independently associated with the primary endpoint in T2DM‐SAHF, independent of age and glycaemic control.ConclusionsThe T2DM‐SAHF has worse subclinical left ventricular function, exercise capacity, and prognosis than other‐SAHF. Impaired GLS, atrial fibrillation, exercise capacity, and obesity are associated with a worse prognosis in T2DM‐SAHF but not in other‐SAHF.

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Section: Discussionmentioning

confidence: 98%

Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies

Wang¹,

Yang²,

Nolan³

et al. 2018

ESC Heart Failure

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“…The software then automatically captured multiple local myocardial acoustic markers and tracked their displacement through a cine loop of frames. 10,11 Longitudinal, radial, and circumferential systolic strains were computed from the resulting 2D displacement fields. We created the strain curves, and then we measured the peak systolic strains in individual walls.…”

Section: D Strain Echocardiographymentioning

confidence: 99%

Biventricular Mechanics in Constrictive Pericarditis Comparison With Restrictive Cardiomyopathy and Impact of Pericardiectomy

Kusunose

Dahiya

Popović

et al. 2013

Circ: Cardiovascular Imaging

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100

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Background-The aim of our study was to compare myocardial mechanics of constrictive pericarditis (CP) with restrictive cardiomyopathy (RCM), or healthy controls; to assess the impact of pericardial thickening detected by cardiac magnetic resonance on regional myocardial mechanics in CP; and to quantitate the effect of pericardiectomy on myocardial mechanics in CP. Methods and Results-Myocardial mechanics were evaluated by 2-dimensional speckle tracking in 52 consecutive patients with CP who underwent cardiac magnetic resonance examination before pericardiectomy, 35 patients with RCM, and 26 control subjects. CP patients had selectively depressed left ventricular (LV) anterolateral wall strain (LWS) and right ventricular (RV) free wall longitudinal systolic strain (FWS) but preserved LV septal wall systolic strain (SWS

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“…Further adjustment of the ROI was performed to ensure that all of the myocardial regions were included. 21 Next, the software captured the myocardium, automatically tracked its motion and thickening on subsequent frames. Finally, the myocardium in each apical view was divided into 6 segments.…”

Section: Speckle Tracking Imaging (Sti)mentioning

confidence: 99%

Tissue Doppler Imaging Dyssynchrony Parameter Derived From the Myocardial Active Wall Motion Improves Prediction of Responders for Cardiac Resynchronization Therapy

Sakamaki

Seo

Ishizu

et al. 2012

Circ J

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Validation of Longitudinal Peak Systolic Strain by Speckle Tracking Echocardiography With Visual Assessment and Myocardial Perfusion SPECT in Patients With Regional Asynergy

Cited by 39 publications

References 28 publications

Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies

Variations in subclinical left ventricular dysfunction, functional capacity, and clinical outcomes in different heart failure aetiologies

Biventricular Mechanics in Constrictive Pericarditis Comparison With Restrictive Cardiomyopathy and Impact of Pericardiectomy

Tissue Doppler Imaging Dyssynchrony Parameter Derived From the Myocardial Active Wall Motion Improves Prediction of Responders for Cardiac Resynchronization Therapy

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