2012
DOI: 10.3171/2011.12.focus11280
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Validation of frontal near-infrared spectroscopy as noninvasive bedside monitoring for regional cerebral blood flow in brain-injured patients

Abstract: Object Near-infrared spectroscopy (NIRS) offers noninvasive bedside measurement of direct regional cerebral arteriovenous (mixed) brain oxygenation. To validate the accuracy of this monitoring technique, the authors analyzed the statistical correlation of NIRS and CT perfusion with respect to regional cerebral blood flow (CBF) measurements. Methods The authors retrospectively reviewed all cases in which … Show more

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Cited by 93 publications
(82 citation statements)
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“…13,18 NIRS measures the content of oxygenated hemoglobin in tissues and depends on arterial partial pressure of oxygen (PaO 2 ) on the one side 1,14 and CBF on the other side. 16,21,22 Transcutaneous NIRS measurement has been validated by comparison with xenon and perfusion CT. 21,22 PaCO 2 was the only variable parameter in the present study. In particular, the arterial oxygen saturation and PaO 2 remained constant.…”
Section: Discussionmentioning
confidence: 99%
“…13,18 NIRS measures the content of oxygenated hemoglobin in tissues and depends on arterial partial pressure of oxygen (PaO 2 ) on the one side 1,14 and CBF on the other side. 16,21,22 Transcutaneous NIRS measurement has been validated by comparison with xenon and perfusion CT. 21,22 PaCO 2 was the only variable parameter in the present study. In particular, the arterial oxygen saturation and PaO 2 remained constant.…”
Section: Discussionmentioning
confidence: 99%
“…The disadvantages of NIRS technology is that it provides only "regional" saturation of oxygen probe information, similar to other, typically invasive, neurointensive care unit probes such as Licox PbO 2 , intracranial pressure probes, or Hemedex cerebral blood flow sensors. Despite these limitations, we believe that NIRS probes have the potential to be useful for managing patients with stroke and NIRS regional saturation of oxygen correlates with CT perfusion-derived regional cerebral blood flow 2 …”
Section: To the Editormentioning
confidence: 99%
“…Одними из наиболее информативных методов, позволяющих выявить ишемию ГМ, являются пер-фузионная компьютерная томография (КТ) и инфра-красная церебральная спектроскопия [2].…”
unclassified
“…Учитывая эти факты, взаимосвязь между уровнем сатурации ткани ГМ (cerebral tissue oxygen saturation -SctO 2 ) и состоянием микроциркуляции в ГМ представляется весьма вероятной. Вместе с тем, исследования по данной проблеме малочисленны [10] и касаются лишь острого нарушения кровооб-ращения ГМ [2].…”
unclassified
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