Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy

Spallone, Vincenza; Morganti, Roberto; D’Amato, Cinzia; Greco, Carla; Cacciotti, Laura; Marfia, Girolama Alessandra

doi:10.1111/j.1464-5491.2011.03500.x

Cited by 215 publications

(185 citation statements)

References 29 publications

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“…It has four questions; the two first include seven sensorial descriptors that characterize NP (burning; painful cold sensation; electric shock; tingling; pricking tugging; numbness and itching). The other two questions relate to the physical examination to assess the indicative signs of neurological injury (hypoesthesia to the touch; hypoesthesia to needle stick and brushing) 19 . Participants answered "yes" or "no" to all items.…”

Section: Methodsmentioning

confidence: 99%

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

Aguiar

Ramos

Bichara

2018

Brazilian Journal of Pain

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Section: Methodsmentioning

confidence: 99%

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

Aguiar

Ramos

Bichara

2018

Brazilian Journal of Pain

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“…Patients were questioned by the authors. The Douleur Neuropathique 4 (DN4) questionnaire for neuropathic pain evaluation was used in this survey, which has been well evaluated in numerous studies (Table 1) [7,8].…”

Section: Methodsmentioning

confidence: 99%

The Prevalence Of Acute Neuropathic Pain After Surgery In Hospital Of Lithuanian University Of Health Sciences Kaunas Clinics

et al. 2017

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SummaryBackground. Acute neuropathic pain can be one of the post-surgical pain components, which is often under-recognized and complicated to treat. The prevalence of pain with neuropathic characteristics in general population is about 6 -8%. Moreover, it might to progress and become as a persistent pain and cause a disability. This type of study has never been performed in Lithuania. Methods. Investigators conducted a survey, which consisted of the following visual and verbal analogue and Dolour Neuropathique 4 scales to identify pain intensity and neuropathic pain after surgery. Risk factors of neuropathic pain were evaluated with Hospital Anxiety and Depression scale, demographic characteristics and data, which represents possible risk factors. Results. The survey included 170 participants: 68 males (40%) and 102 females (60%). Average age of patients was 59.66 years (SD 15.9). During the first day after surgery 7.1% patients felt neuropathic pain, on the second day -8.2%, and the third postoperative day -7.6% of patients. A prevalence of neuropathic pain depends on gender and anxiety before surgery. Conclusion. A prevalence of acute neuropathic pain after surgery in Hospital of Lithuanian University of Health Sciences is 7 -8%. The risk factors of neuropathic pain development are patient's gender and anxiety before surgical procedure.

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“…It comprises 10 items; a positive item (indicating presence) is assigned a score of 1, while a negative item (indicating absence) is assigned 0. A diagnosis of neuropathic pain is indicated by a total of at least 4 when the scores are summed across all 10 items [11]. About 7 of the 10 items relate to the description of the pain and the associated, abnormal, sensations.…”

Section: Dn4 (Douleur Neuropathique-4 or 'Neuropathic Pain-4')mentioning

confidence: 99%

“…The sensations are numbness, itching, tingling, and "pins and needles." The remaining three items, tactile dynamic allodynia (using a soft brush), pinprick hypoesthesia (using a toothpick), and touch hypoesthesia (using a soft brush) are evaluated in the painful area [11].…”

Section: Dn4 (Douleur Neuropathique-4 or 'Neuropathic Pain-4')mentioning

confidence: 99%

Factors Influencing the Severity of Pain in Patients With Peripheral Diabetic Neuropathy

Al-Mahmood

Razak

Ahmad

et al. 2017

Asian J Pharm Clin Res

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Objective: The principal aim of this study was to identify factors influencing the severity of peripheral diabetic neuropathy pain (PDNP), a symptom of the common neurological complication of diabetes mellitus, and peripheral diabetic neuropathy. Methods:A cross-sectional study was performed using two self-administered questionnaires among subjects recruited from outpatient clinics at Hospital Tengku Ampuan Afzan, Kuantan, Malaysia. The Neuropathic Pain-4 tool was used to evaluate the presence of PDNP, and the Short-Form McGill Pain Questionnaire (MPQ) was used to characterize and determine the severity of PDNP. Sociodemographic and clinical data were collected from the patients.Results: The MPQ indicated that most patients reported experiencing mild pain for all sensory pain descriptors other than throbbing and aching (mostly reported to be moderate) and hot-burning (mostly reported to be no pain). The severity of pain was found to be significantly related to the length of time for which the patients had suffered from diabetes in those patients who had been diagnosed over 10 years previously (p=0.04). Indian patients reported a higher severity of pain overall (p=0.04). No significant relationship was found between pain severity and any of the following factors: Type of diabetes (I or II), gender, smoking status, alcohol consumption, obesity, medication taken, or presence of other diseases. Conclusion:In this study, most patients with PDNP reported the severity of the pain to be "mild." The pain severity may be influenced by a patient's ethnicity and the length of time for which they have suffered from diabetes.

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Validation of DN4 as a screening tool for neuropathic pain in painful diabetic polyneuropathy

Abstract: This is the first validation study of DN4 for painful diabetic polyneuropathy, which supports its usefulness as both a screening tool for neuropathic pain in diabetes and a reliable component of the diagnostic work up for painful diabetic polyneuropathy.

Cited by 215 publications

References 29 publications

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

Detection of pain with neuropathic characteristics in patients with diabetes mellitus assisted in primary care units

The Prevalence Of Acute Neuropathic Pain After Surgery In Hospital Of Lithuanian University Of Health Sciences Kaunas Clinics

Factors Influencing the Severity of Pain in Patients With Peripheral Diabetic Neuropathy

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