Validation of direct cortical stimulation in presurgical evaluation of epilepsy

Ley, Miguel; Peláez, Núria; Príncipe, Alessandro; Langohr, Klaus; Zucca, Riccardo; Rocamora, Rodrigo

doi:10.1016/j.clinph.2022.02.006

Cited by 5 publications

(1 citation statement)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Frequently, depth and subdural electrodes are used in complementary fashion during challenging cases, locating the SOZ in up to 95% of cases when combined, with an overall haemorrhage risk of less than 5% [35 ▪ ]. Although some authors have suggested that stimulation-evoked seizures may reflect electrical cortical spread rather than epileptogenicity [36], a recent study has found that true habitual electroclinical seizures triggered by DCS have a specificity of 96% and an accuracy of 89% in localizing the SOZ, showing that resection of electrode contacts involved in triggering habitual seizures is associated with favourable seizure outcomes [37]. Nonhabitual stimulation-triggered seizures should not be considered for clinical decisions, as all cortical areas have potential epileptogenicity when DCS is continuously applied.…”

Section: Recent Innovations In Surgical Techniquesmentioning

confidence: 99%

Recent advances in epilepsy surgery

Medina-Pizarro

Spencer²,

Damisah³

2023

Current Opinion in Neurology

View full text Add to dashboard Cite

Purpose of reviewTechnological innovations in the preoperative evaluation, surgical techniques and outcome prediction in epilepsy surgery have grown exponentially over the last decade. This review highlights and emphasizes relevant updates in techniques and diagnostic tools, discussing their context within standard practice at comprehensive epilepsy centres. Recent findingsHigh-resolution structural imaging has set an unprecedented opportunity to detect previously unrecognized subtle abnormalities. Machine learning and computer science are impacting the methodologies to analyse presurgical and surgical outcome data, building more accurate prediction models to tailor treatment strategies. Robotic-assisted placement of depth electrodes has increased the safety and ability to sample epileptogenic nodes within deep structures, improving our understanding of the seizure networks in drugresistant epilepsy. The current available minimally invasive techniques are reasonable surgical alternatives to ablate or disrupt epileptogenic regions, although their sustained efficacy is still an active area of research.

show abstract

Section: Recent Innovations In Surgical Techniquesmentioning

confidence: 99%