Validation of computational fluid dynamics of shake flask experiments at moderate viscosity by liquid distributions and volumetric power inputs
Carl Dinter,
Andreas Gumprecht,
Matthias Alexander Menze
et al.
Abstract:Computational fluid dynamics (CFD) has recently become a pivotal tool in the design and scale-up of bioprocesses. While CFD has been extensively utilized for stirred tank reactors (STRs), there exists a relatively limited body of literature focusing on CFD applications for shake flasks, almost exclusively concentrated on fluids at waterlike viscosity. The importance of CFD model validation cannot be overstated. While techniques to elucidate the internal flow field are necessary for model validation in STRs, th… Show more
“…The flow field of filling processes of different structures were analyzed by FLUENT software using the Volume of Fluid (VOF) model [20][21][22]. The typical crosssectional mutation structure of the casting is extracted as shown in Fig.…”
Section: Numerical Simulation Of the Filling Processes Of Different S...mentioning
In order to ensure the filling integrity of complex counter-gravity casting and improve metallurgical quality, it is necessary to shorten the filling time while avoiding air entrainments. To address this contradiction, a novel nonlinear pressurization method was proposed in this study. Through systematically analyzing the relationship between critical filling speed and stable filling height, a criterion for iterative calculation of nonlinear pressurization speed was established, and an empirical expression between nonlinear pressurization speed and the filling height was obtained. Based on the empirical expression, a nonlinear pressurization curve can be designed according to the casting structures and initial pressurization speeds. The above nonlinear pressure curve design method was validated through water simulation. It was proved that the nonlinear pressure curve can shorten the filling time while avoiding air entrainments. It provides important processing control method for improving the low-pressure casting performance of complex castings.
“…The flow field of filling processes of different structures were analyzed by FLUENT software using the Volume of Fluid (VOF) model [20][21][22]. The typical crosssectional mutation structure of the casting is extracted as shown in Fig.…”
Section: Numerical Simulation Of the Filling Processes Of Different S...mentioning
In order to ensure the filling integrity of complex counter-gravity casting and improve metallurgical quality, it is necessary to shorten the filling time while avoiding air entrainments. To address this contradiction, a novel nonlinear pressurization method was proposed in this study. Through systematically analyzing the relationship between critical filling speed and stable filling height, a criterion for iterative calculation of nonlinear pressurization speed was established, and an empirical expression between nonlinear pressurization speed and the filling height was obtained. Based on the empirical expression, a nonlinear pressurization curve can be designed according to the casting structures and initial pressurization speeds. The above nonlinear pressure curve design method was validated through water simulation. It was proved that the nonlinear pressure curve can shorten the filling time while avoiding air entrainments. It provides important processing control method for improving the low-pressure casting performance of complex castings.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.