Validation of cardiac image derived input functions for functional PET quantification
Murray Bruce Reed,
Patricia Anna Handschuh,
Clemens Schmidt
et al.
Abstract:Functional PET (fPET) is a novel technique for studying dynamic changes in brain metabolism and neurotransmitter signaling. Accurate measurement of the arterial input function (AIF) is crucial for quantification of fPET but traditionally requires invasive arterial blood sampling. While, image-derived input functions (IDIF) offer a non-invasive alternative, they are afflicted by drawbacks stemming from limited spatial resolution and field of view. Therefore, we conceptualized and validated a scan protocol for b… Show more
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