Validation of Appropriate Use Criteria for Coronary Computed Tomographic Angiography for Chest Pain Evaluation in a Tertiary Care Emergency Room

Abstract

Purpose: Appropriate use criteria (AUC) defines the appropriateness of imaging procedures for specific clinical scenarios to promote evidence-based utilization and improve cost-effective care. The goal of this study was to assess the diagnostic yield and downstream health care resource utilization according to the AUC categorization for coronary computed tomography angiography (CCTA) in emergency department (ED) patients presenting with chest pain. Materials and Methods: A total of 789 consecutive patients in the ED with chest pain and no known coronary artery disease (CAD) who underwent CCTA were classified as appropriate, uncertain, or inappropriate use according to the 2010 AUC. We abstracted index and 30-day data from the electronic medical record to determine diagnostic yield (rate of obstructive CAD and revascularization) and health care resource utilization (downstream stress test and 30-d hospital return rate). Results: Rates of appropriate, uncertain, and inappropriate utilization were 48.4%, 48.8%, and 2.8%. Among appropriate, uncertain, and inappropriate classifications, rates of obstructive CAD were 9%, 8%, and 32% (P=0.002); rates of revascularization were 3%, 1%, and 36% (P<0.001); downstream stress test utilization rates were 5% versus 5% versus 14% (P=0.17), and 30-day hospital return rates were 6% versus 6% versus 5% (P>0.99), respectively. Conclusions: Appropriate and uncertain uses were associated with low diagnostic yield compared with inappropriate use; however, our findings do not demonstrate differences between appropriate use categories with respect to downstream health care resource utilization. Further studies are needed to define the role of AUC for CCTA in the ED setting.

Bodyweight-adjusted Contrast Media with Shortened Injection Duration for Step-and-Shoot Coronary Computed Tomography Angiography to Acquire Improved Image Quality

“…CCTA has rapidly become an effective method for detecting CAD over the last decade. [2][3][4] Better image quality directly leads to more accurate diagnoses and treatments, while appropriate ICM administration is an influencing factor that helps improve the image quality while helping to protect renal function, 5,6 decrease the risk of possible allergic reactions and hyperthyroidism, 7 and save costs by avoiding waste. 8 Many recent studies have shown that lower ICM administration in CCTA imaging can be achieved without sacrificing the image quality with different kinds of CT scanners.…”

“…According to the Heart Disease and Stroke Statistics (2022 update),1 coronary artery disease (CAD) is a common disease of the cardiovascular system, the incidence of which has been increasing year by year in the recent years, and it is being seen in the younger population. CCTA has rapidly become an effective method for detecting CAD over the last decade 2–4. Better image quality directly leads to more accurate diagnoses and treatments, while appropriate ICM administration is an influencing factor that helps improve the image quality while helping to protect renal function,5,6 decrease the risk of possible allergic reactions and hyperthyroidism,7 and save costs by avoiding waste 8…”