“…The 12 PROMIS measures evaluated for validity included physical health (Fatigue, 32,33 Physical Function, 34,35 Sleep Disturbance, 36,37 Sleep-Related Impairment 36,37 ), mental health (Depression, 38,39 Anxiety, 38 Cognitive Function 40,41 ), and social health (Social Function: Ability to Participate in Social Roles, 42 Satisfaction With Social Roles and Activities 42 ; Social Relationships: Emotional, Informational, and Instrumental Social Support 42 ). The PROs, clinician ratings, performance tests, and clinical adverse events that were used as validity indicators included KCCQ-12, 14,15 EQ-5D-3L, 12,13 Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being 12-item scale, 43,44 PROMIS Overall Quality of Life item, 20 New York Heart Association functional classification, 45 Health Literacy Assessment Using Touchscreen Technology, 46,47 6-minute walk test, [48][49][50][51] trail making test, part B, [52][53][54] and neurological dysfunction. 11…”