Validation of a Rapid Quantitative Method for the Residues of Nitrofuran Metabolites in Loach by Accelerated Solvent Extraction and HPLC Triple Quadrupole Mass Spectrometry

Ryu, Eun Chae; Han, Yun-jeong; Park, Seong-soo; Lim, Chul-Joo; Choi, Sun-Ok; Park, Taesung

doi:10.13103/jfhs.2016.31.2.85

Cited by 1 publication

(2 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The results of the percentage of nitrofurans residue are shown in Table 5. In general, matrix effects are an issue of concern in nitrofuran metabolite analysis studies (Ryu et al, 2016). Matrix effects occurred due to co-eluting interferences compounds that impact the ionisation of the chromatographic of the target analytes (Panuwet et al, 2016).…”

Section: Hplc Analysis Of Nitrofurans Residuementioning

confidence: 99%

“…According to Tsai et al (2010), in recent years, several laboratories have relied on a high-performance liquid chromatography-diode array detector (HPLC-DAD) to quantify nitrofurans metabolite residues. According to Ryu et al (2016), HPLC is the optimal method for separating and studying nitrofurans metabolites. The most significant benefit is that it can be used with a wide range of analytes, from small organic compounds and ions to large macromolecules and polymers (Pacholak et al, 2020).…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Dual Extraction Methods for Nitrofuran Antibiotics Residues; Furaltadone, Furazolidone, and Nitrofurazone from Biotransformation Assay

Zainal Ariffin

2023

ASMScJ

View full text Add to dashboard Cite

This study aims to extract nitrofuran antibiotics residues, furaltadone, furazolidone, nitrofurazone from biotransformation assays by local Aspergillus tamarii KX610719.1. Nitrofuran antibiotics were quantified by using a high-performance liquid chromatography-diode array detector (HPLC-DAD). Liquid-liquid extraction (LLE) and solid phase extraction (SPE) were employed to extract nitrofurans residue for the optimal purification and cleaned up procedures. In this study, a good linearity with the coefficient of determination R² value of 0.9951 – 0.9972 mg/L with the concentration range of 1 to 50 mg/L nitrofuran antibiotics was achieved. The relative standard deviation (RSD) for triplicate nitrofurans assay were less than 10.0 %. The limit of detection (LOD) and limit of quantification (LoQ) of furazolidone, furaltadone and nitrofurazone were found to be in the range of 2.37 – 10.56 mg/L and 7.17 – 31.99 mg/L, respectively. Moreover, the recovery of the nitrofuran antibiotics investigated in biotransformation assays ranged from 70.0 % - 88.0 %. The developed technique was effectively employed to determine nitrofurans residue in biotransformation assays and demonstrated remarkable clean-up capacity.

show abstract

Section: Hplc Analysis Of Nitrofurans Residuementioning

confidence: 99%