Validation of a prediction score model to distinguish acute coronary syndromes from other conditions causing raised cardiac troponin T levels

Abstract

A prediction score model using simple clinical variables has been validated, and this can help clinicians in distinguishing patients with ACS from other non-ACS conditions.

Early and late mortality in hospitalised patients with raised cardiac troponin T

“…These patients were likely to have acute decompensating medical conditions which could cause a fluctuating pattern in their troponin level, thus potentially leading to a diagnosis of type 2 MI pending on the presence and interpretation of symptoms, electrocardiographic changes or cardiac wall motion abnormalities. We have previously shown in a different hospitalised cohort that type 1 MI had a better 1-year survival than type 2 MI (33.8% vs 65.0%; p=0.011) 16. Despite the continuing evolution of guidelines in the diagnosis of MI and promising new treatments for type 1 MI, management of type 2 MI lacks consensus guidelines and clinical trial evidence, and has been left at the discretion of individual clinicians 17.…”

Perioperative serum troponin I levels are associated with higher risk for atrial fibrillation in patients undergoing coronary artery bypass graft surgery

“…The measurements of cardiac troponins have become the gold standard for detecting myocardial damage [4] and risk stratification in patients with acute coronary syndrome [5]. A few studies have documented that elevated levels of pre-or postoperative cardiac troponin I (cTnI) are associated with increased operative death and adverse events after CABG [2,6].…”