Validation of a novel high‐intensity <scp>LED</scp> light source for skin phototesting at 365 nm

Wan, Pengjie; Edwards, Chris; Zheng, Jie; Anstey, Alex

doi:10.1111/j.1600-0781.2011.00641.x

Cited by 3 publications

(1 citation statement)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This dose is selected for two reasons; 1) 99% of storage modulus is achieved by 20 J cm -2 (as evident from photorheometry results; Fig. 1 a,c,d) and 2), the maximum exposure dose of 20 J cm -2 is the upper limit to prevent erythematic response on skin as defined by the guidelines issued by International Commission on Non-Ionizing Radiation Protection for UVR exposure [31,32]. Lap shear stress/strain profiles are shown in Fig.…”

Section: High Mn Peg Reinforcement Increases Lap Shear Adhesion Strengthmentioning

confidence: 99%

Tertiary blends of PAMAM/PEG/PEG tissue bioadhesives

Shah

Djordjević

Steele

2020

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

Section: High Mn Peg Reinforcement Increases Lap Shear Adhesion Strengthmentioning

confidence: 99%

Tertiary blends of PAMAM/PEG/PEG tissue bioadhesives

Shah

Djordjević

Steele

2020

Journal of the Mechanical Behavior of Biomedical Materials

View full text Add to dashboard Cite

Equipment developed for simplifying routine phototesting in dermatology

Wulf,

Heydenreich,

Philipsen

2023

Photochem Photobiol Sci

View full text Add to dashboard Cite

Some people react abnormally when exposed to sunlight by getting easily burned or develop a rash. When testing a patient’s level of photosensitivity in the clinic, the UVR dose to provoke erythema is determined by the minimal erythema dose (MED) test. Subsequently, a photoprovocation test is performed to detect abnormal skin reactions by daily exposing the skin to UVR for several consecutive days. Associated problems in MED testing include choice of an even skin area for testing, patients keeping still during the test, testing with different UVR doses simultaneously, and securing clear borders of erythema. To address these issues, a MED Test Patch was developed which adheres closely to the skin to ensure sharp erythema borders and provides six irradiation fields with decremental doses of 20%. For MED testing, we constructed a solar simulator and LED lamps with peak emissions at 309 and 370 nm, small enough to be mounted directly on to the MED Test Patch and accommodate patient movements. These lamps and a 415 nm LED can also be used for provocation testing which is best performed on the back where the skin is assumed to have identical UVR sensitivity, and the area is large enough for adjacent MED and provocation test fields. Reading of erythema is still performed by visual and tactile evaluation. The UVA and UVB MED test can be performed in 1 h. The advantage of these developments is an easy-to-use, standardized test method with improved accuracy of the results. Graphical Abstract

show abstract