Validation of a new quality of life questionnaire for benign prostatic hyperplasia

Epstein, Robert S.; Deverka, Patricia A.; Chute, Christopher G.; Panser, Laurel A.; Öesterling, Joseph E.; Lieber, Michael M.; Schwartz, Skai W.; Patrick, Donald L.

doi:10.1016/0895-4356(92)90205-2

Cited by 174 publications

(100 citation statements)

References 13 publications

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“…M e d ia n p a tie n t d a ta by co u n try separately a n d for the total sa m p le w ith 5 th a n d 9 * Urination at least 2 times a night, f Urination at least 9 times a day. shown in tables 2 and 3.…”

Section: Resultsmentioning

confidence: 99%

The International Continence Society “Benign Prostatic Hyperplasia” Study: International Differences in Lower Urinary Tract Symptoms and Related Bother

et al. 1997

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Purpose: We investigated the international differences in the reporting of lower urinary tract symptoms and related bother in patients with symptoms suggestive of bladder outlet obstruction.Materials and Methods: Multiple logistic regression analysis was used to evaluate interna tional differences in the reporting of lower urinary tract symptoms and related bother in 1,271 patients from 12 countries who participated in the International Continence Society "benign prostatic hyperplasia" study.Results: Country of origin was significantly associated with the prevalence of a large number of lower urinary tract symptoms (10 of 20), even after adjusting for potentially confounding variables, including physical and socio-demographic factors. Country of origin was also signifi cantly associated with the reporting of bother but for a much smaller number of symptoms (2).Conclusions: In different countries lower urinary tract symptoms may be reported to different extents. Therefore, the results of studies in particular countries may not be generally applicable to other countries. It is likely that symptom scores will conceal this variation, necessitating consid eration of individual symptoms (as in the International Continence Society "benign prostatic hyper plasia" study) or the development of country specific scoring systems. An alternative would be to focus on bother, which appeared to be much less sensitive to international differences.

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Section: Resultsmentioning

confidence: 99%

The International Continence Society “Benign Prostatic Hyperplasia” Study: International Differences in Lower Urinary Tract Symptoms and Related Bother

et al. 1997

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“…The SPI and BSIA questionnaires have been demonstrated to be valid and reliable QOL instruments. 12,13 The BPWB questionnaire was developed specifically for these studies, as no established questionnaire at the time provided a comprehensive assessment of the emotional consequences of urinary symptoms. The BPWB questionnaire measures the extent to which urinary problems are embarrassing, frustrating or annoying.…”

Section: Methodsmentioning

confidence: 99%

Dutasteride significantly improves quality of life measures in patients with enlarged prostate

O’Leary

Roehrborn²,

Black

2007

Prostate Cancer Prostatic Dis

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The purpose of this study was to determine the effect of dutasteride on quality of life of men with lower urinary tract symptoms associated with enlarged prostate or benign prostatic hyperplasia (BPH) as measured by symptom problem index (SPI), BPH-specific interference with activities (BSIA), BPH-specific psychological well-being (BPWB) and BPH-specific lifestyle adaptations (BSLA). Data were derived from three randomized, double-blind studies conducted in 4325 men treated with placebo or dutasteride (0.5 mg/day). Primary analyses included changes from baseline in mean SPI, BSIA, BPWB and BSLA scores. Men treated with dutasteride showed significant improvements in SPI, BSIA, BPWB and BSLA scores compared with placebo.

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“…10 The primary tools used to determine the presence of LUTS include the International Prostate Symptom Score (IPSS), the American Urological Association (AUA) Symptom Index, 11 the Danish Prostate Symptom Score (DAN-PSS), 12 and the International Continence Society questionnaire. 13 Other tools that measure the effect of LUTS on quality of life include the BPH Impact Index, 14 the UROLIFE Scale, 15 the BPH Health-related Quality of Life Survey, 16 and the bothersomeness question included in the IPSS (Bother Score).…”

Section: Components Of Quality Of Life In Bphmentioning

confidence: 99%

Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

Carbone

Hodges

2003

Int J Impot Res

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Therapies for benign prostatic hyperplasia (BPH) may either improve or exacerbate sexual function with an ensuing impact on quality of life. Here we review a total of 73 papers on medical therapies for BPH with a focus on the effects of different pharmacological agents on sexual function. For example, certain a 1 -adrenergic receptor blockers may improve erectile function; however, ejaculatory dysfunction with one of these agents, tamsulosin, occurs at a rate of 4-18%, rising to 30% with long-term use. In addition, treatment with the 5a-reductase inhibitor finasteride is associated with problems of ejaculation (2.1-7.7%), erection (4.9-15.8%), and libido (3.1-5.4%). Such significant and undesirable complications in relation to sexual function produce a welldocumented negative impact on quality of life. Thus, optimal treatment for men with BPH requires the use of agents that demonstrate efficacy and safety with fewer sexual side effects.

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Validation of a new quality of life questionnaire for benign prostatic hyperplasia

Cited by 174 publications

References 13 publications

The International Continence Society “Benign Prostatic Hyperplasia” Study: International Differences in Lower Urinary Tract Symptoms and Related Bother

The International Continence Society “Benign Prostatic Hyperplasia” Study: International Differences in Lower Urinary Tract Symptoms and Related Bother

Dutasteride significantly improves quality of life measures in patients with enlarged prostate

Medical therapy for benign prostatic hyperplasia: sexual dysfunction and impact on quality of life

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