Validation of a musculo-skeletal model of the mandible and its application to mandibular distraction osteogenesis

Validation of a musculoskeletal model of wheelchair propulsion and its application to minimizing shoulder joint forces

“…Historically, comparing the calculated muscle activities of biomechanical models with experimental EMG has long been an accepted means of model validation (Crowninshield, 1978). The mean absolute error (MAE), previously used to quantitatively validate a computational musculoskeletal model (de Zee et al, 2007), was calculated for each muscle's activity envelope with the following equation:…”

A dynamic model of jaw and hyoid biomechanics during chewing

“…Other limitations included simplified Table 1. tooth guidance and bolus properties, sparse representation of the infra-hyoid muscles, and omission of the tongue. Models of the human jaw are difficult to validate (Hannam, 2005;Leon et al, 2006;Peck and Hannam, 2007;de Zee et al, 2007) since detailed exploration of the muscles and joints is restricted technically and ethically. Like others, our model is at best a working hypothesis strengthened by its performance of tasks with outcomes falling within normal ranges (Hannam, 2005;Peck and Hannam, 2007).…”

“…As jaw biomechanics are difficult to study directly, modelling has become an important investigative tool (van Eijden, 2000;Koolstra, 2002;Hannam, 2005;Koolstra and van Eijden, 1995, 1997, 2005Peck and Hannam, 2007;van Eijden and Koolstra, 1998;Peck et al, 2000Peck et al, , 2002Sanguineti et al, 1998;Hansma et al, 2006;Stavness et al, 2006;Leon et al, 2006;de Zee et al, 2007). Simulations of the chewing cycle are rare however.…”

Prediction of the articular eminence shape in a patient with unilateral hypoplasia of the right mandibular ramus before and after distraction osteogenesis—A simulation study

“…The present model has many similarities with the generic, symmetric mandible model, which has been described recently (de Zee et al, 2007), with the main difference being that the present model is asymmetric due to the hypoplasia of the right ramus and condyle. The insertions of the different muscle fascicles were determined with the help of the MRI and CT scans of the patient analyzed by Cattaneo et al (2005).…”

“…Bearing in mind the results of Nickel et al (1988), Trainor et al (1995) and Iwasaki et al (2003) it seems reasonable also in this clinical case to hypothesize that these differences in eminence morphology between left and right side are consistent with minimisation of joint loads. In order to test this hypothesis an estimation of the individual muscle forces and the reaction forces in the TMJ for a given bite force with a varying articular eminence shape is In this paper we shall present a patient-specific version of the model by De Zee et al (2007). The model represents the patient previously analyzed by Cattaneo et al (2005).…”