Validation of a multimodal algorithm for diagnosing giant cell arteritis with imaging

Hage, Rabih; Charbonneau, F.; Vignal, Catherine; Sené, Thomas; Picard, Hervé; Leturcq, Tifenn; Zuber, Kévin; Belangé, G; Affortit, Aude; Sadik, Jean-Claude; Savatovsky, Julien; Clavel, Gaëlle

doi:10.1016/j.diii.2021.09.008

Cited by 15 publications

(22 citation statements)

References 48 publications

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“…The significant features are represented by circumferential mural thickening and wall edema (the last one is enhanced in T2 sequences). Because MRI does not need iodinated contrast or ionising radiation, it has been utilized for repetitive exams [ 39 , 65 , 66 ].…”

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

“…Lecler et al conducted a study whose main purpose was to identify which combination of imaging modalities should be used to obtain the best diagnostic performance for the non-invasive diagnosis of GCA [ 66 ]. Patients underwent high-resolution 3 T magnetic resonance imaging (MRI), temporal and extracranial arteries US and retinal angiography (RA), prior to TAB.…”

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

“…The diagnostic accuracy of each imaging modality alone, then a combination of several imaging modalities, was evaluated. The diagnostic algorithm with the overall best diagnostic performance was the one starting with MRI, followed either by US or RA, yielding 100% sensitivity (22/22; 95% CI: 85−100%), 100% (15/15; 95% CI:78−100) and 100% accuracy (37/37; 95% CI: 91−100) [ 66 ]. They concluded that the use of MRI as the first imaging examination followed by either US or RA reaches high degrees of performance for the diagnosis of GCA and is recommended in daily practice [ 66 ].…”

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

“…b. For the assessment of small retro-orbital arteries (CRA, PCAs, OA) in patients with GCA with eye involvement, we can utilize two types of techniques: an invasive one (the fluorescein angiography/retinal angiography (RA)) and diverse noninvasive imaging methods, such as Color Doppler ultrasonography of the retrobulbar vessels, structural Optical Coherence Tomography (OCT) of the ONH and OCT angiography [ 9 , 10 , 11 , 12 , 13 , 14 , 15 , 50 , 66 , 76 ].…”

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

“…studied which association of imaging techniques should be utilized for the most accurate diagnosis of clinically suspected GCA. They concluded that the best diagnostic algorithm for this purpose consisted in the use of high-resolution 3T magnetic resonance imaging, followed by either extracranial arteries (including temporal and other rami of ECAs) US exam or retinal angiography, before temporal artery biopsy (TAB) [ 66 ].…”

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

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Ultrasound Technologies and the Diagnosis of Giant Cell Arteritis

Jianu

Jianu²,

Dan

et al. 2021

Biomedicines

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Giant cell arteritis (GCA) is a primary autoimmune vasculitis that specifically affects medium-sized extracranial arteries, like superficial temporal arteries (TAs). The most important data to be considered for the ultrasound (US) diagnosis of temporal arteritis are stenosis, acute occlusions and “dark halo” sign, which represent the edema of the vascular wall. The vessel wall thickening of large vessels in GCA can be recognized by the US, which has high sensitivity and is facile to use. Ocular complications of GCA are common and consist especially of anterior arterial ischemic optic neuropathies or central retinal artery occlusion with sudden, painless, and sharp loss of vision in the affected eye. Color Doppler imaging of the orbital vessels (showing low-end diastolic velocities and a high resistance index) is essential to quickly differentiate the mechanism of ocular involvement (arteritic versus non-arteritic), since the characteristics of TAs on US do not correspond with ocular involvement on GCA. GCA should be cured immediately with systemic corticosteroids to avoid further visual loss of the eyes.

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Section: Us and Others Imaging Techniquesmentioning

confidence: 99%

Section: Us and Others Imaging Techniquesmentioning

confidence: 99%