Table 1 Glossary of Terms Related to Weight Loss and FrailtyFrailty: The presence of three or more of the following: unintentional weight loss, self-reported exhaustion, weakness, slow gait speed, and low physical activity (1). Nutritional Frailty: The disability that occurs in old age due to loss of lean body mass (sarcopenia) and rapid, unintentional weight loss. Food intake is reduced and loss of body weight and lean mass is precipitous. Sarcopenia: The loss of muscle mass and strength that occurs with aging, defined by a value for appendicular muscle mass that is 2 standard deviations or more below the mean for young healthy adults. Cachexia: Weight loss due to a cytokine-mediated response, which can involve anorexia, increased lipolysis, muscle protein breakdown, and nitrogen loss. Wasting: Weight loss that occurs in the absence of cytokine effects. Saropenic-lean: Individuals with sarcopenia who have a percent body fat below sex-specific cutoff values and an approximate BMI of <27 kg/m 2 . Sarcopenic-obese: Individuals with sarcopenia who have a pecent body fat greater than sexspecific cutoff values, approximate BMI of ≥27 kg/m 2 .