Validation and Diagnostic Usefulness of Gastroesophageal Reflux Disease Questionnaire in a Primary Care Level in Mexico

Abstract

Background/Aims Different non-invasive diagnostics strategies have been used to assess patients with gastroesophageal reflux. Gastroesophageal reflux disease (GERD) questionnaire (GerdQ) is a 6-item, easy to use questionnaire that was developed primarily as a diagnostic tool for GERD in primary care. Our aim was to validate and assess diagnostic utility of GerdQ questionnaire in Mexican patients in the primary care setting. Methods The study was performed in 3 phases: (1) a questionnaire translation and comprehension study (n = 20), (2) are a reproducibility and validation study (50 patients and 50 controls) and (3) a study to assess the clinical utility in 252 subjects with GERD symptoms. Diagnostic accuracy was calculated using endoscopy and/or pH-metry as the gold standard. Results Internal consistency measured by the Cronbach’s α coefficient was 0.81 for patients and 0.90 for healthy controls, with a mixed coefficient of 0.93. Reproducibility for GerdQ was very good and its discriminating validity was 88%. Most of the patients with erosive reflux and non-erosive reflux with abnormal pH-metry had scores > 8, meanwhile most of the patients with functional heartburn and hypersensitive esophagus had < 8. Sensitivity, specificity and positive predictive value of GerdQ com -pared to the gold standard were 72%, 72% and 87%, respectively. Conclusions In Mexico, the GerdQ questionnaire Spanish validated version is useful for GERD diagnosis in the primary care setting.

Enfermedad por reflujo gastroesofágico en pacientes con Diabetes Mellitus tipo 1: utilidad de dos cuestionarios auto-aplicables

“…Clinical and biochemical data were recorded at the time of initial assessment. All patients completed the FSSG 10 ( Annex 1 ) and CDQ 14 ( Annex 2 ) questionnaires validated in Spanish. A CDQ questionnaire with a score greater than 4 or FSSG with a score greater than 8, were considered positive for the detection of GERD.…”

“…Both questionnaires have been widely used and validated in different populations, including patients from our country 8 - 10 and patients with type 2 diabetes mellitus 11 , 12 . However, they have not been used in patients with T1D.…”

Usefulness of Robinia pseudoacacia in the Treatment of Gastroesophageal Reflux Disease

“…Patients were asked to review the frequencies of various symptoms which were described by a Likert scale from 0 to 3 for positive symptom problems and from 3 to 0 for negative symptom problems, with a total GerdQ score range from 0 to 18. 7 The GerdQ is a potentially useful tool for family practitioners and other health care professionals in diagnosing and managing GERD without initial specialist referral or endoscopy. 8 Percentage gain in improvement was assessed as:…”

A Randomized Placebo-Controlled N-of-1 Trial: The Effect of Proton Pump Inhibitor in the Management of Gastroesophageal Reflux Disease

“…N-of-1 trials, also known as individual-patient trials or single-patient trials, are double-blinded, multiple-crossover, comparative trials of treatment effect [28]. In this study, the participant is treated with two or more treatments on multiple occasions during the study, allowing the identification of the best treatment for each patient [29]. It is a very useful experimental design for pathologies such as GERD allowing the efficacy of the individual therapeutic interventions in this condition; it could be routinely used in the clinical practice to optimize the PPI treatment for each patient [30,31,32].…”