Val30Met Familial Amyloid Polyneuropathy, Heart Failure, and Chylous Ascites: An Unexpected Combination

Chylous Ascites Due to Hyperthyroidism and Heart Failure

“…Even among patients with CA, SAAG was reported to be effective in distinguishing ascites caused by portal hypertension from ascites due to other etiologies (2-4). In our case, an analysis of the ascitic fluid revealed an elevated SAAG (2.0 g/dL) and protein level (3.1 mg/dL), compatible with the diagnosis of portal hypertension secondary to heart failure; notably, other findings of In addition to the findings of the present case, we reviewed the analytical findings of ascites from the six previously reported cases of CA with heart failure (Table 3) (5,(7)(8)(9)(10)(11). Among these 7 cases, SAAG was described in 5 cases, including 4 with an SAAG !…”

“…These observations suggest that the SAAG and ascitic fluid protein levels might be useful for detecting the cardiac cause in patients with CA. The prognosis of these cases was better than that of cases with CA due to other etiologies, such as malignancy and trauma ( 5 , 7 - 10 ). In the present case, CA improved rapidly after treatment with an antithyroid drug and diuretics.…”

“…Excluding cases with constrictive pericarditis, only six cases of CA associated with heart failure have been reported (5,(7)(8)(9)(10)(11). Some pathophysiological hypotheses have been proposed.…”

“…Hyperthyroidism might be associated with the development of CA, and only two such cases have been reported in the literature (5,6). Furthermore, heart failure has been reported as a reversible cause of CA (5,(7)(8)(9)(10)(11).…”