Vaginal bleeding in a young girl due to primary hypothyroidism

Abstract

When vaginal bleeding occurs in young girls, it is always of clinical importance. The diagnosis should be made with some urgency, so that an appropriate therapy will be given in time. We present a rare case of a 6-year-old girl with primary hypothyroidism, who presented with a history of cyclical vaginal bleeding and precocious puberty while her bone age was delayed. Thyroxine therapy was commenced soon after diagnosis, the bleeding consequently stopped and there was no recurrence after six-month of follow-up.

Hypercalciuria as a Cause of Genital Bleeding in a 6-Year-Old Girl

“…5 Our patient had no clinical evidence of precocious puberty, both clinically and biochemically. Other metabolic endocrine abnormalities, such as hypothyroidism and hyperprolactinemia, 6 can cause vaginal bleeding in this age group, but again this was eliminated through a normal TSH and prolactin. Isolated premature menarche is described in the literature, in which cyclic bleeding occurs in the absence of secondary sexual characteristics.…”