“…Numerous reports have demonstrated the use of the AngioVacÔ system (AngioDynamics Inc, Latham, NY) to debulk and remove vegetations and thrombi prior to and/or during TLE. 11 However, multiple concerns remain about the use of this system in a critically ill patient with high operative morbidities, including portability, vascular complications, size of cannulas for the system, need for system anticoagulation, difficulty steering the catheter, and cost of acquiring/maintaining the system. The IndigoÔ Thrombectomy System (Penumbra, Inc, Alameda, CA) is an aspiration catheter designed to engage the clot and extract it with a continuous vacuum pump.…”