Vacuum-Assisted Closure in the Treatment of Degloving Injuries

Meara, John G.; Guo, Lifei; Smith, Jeff D.; Pribaz, Julian J.; Breuing, Karl H.; Orgill, Dennis P.

doi:10.1097/00000637-199906000-00002

Cited by 97 publications

(55 citation statements)

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“…Negative pressure wound therapy (NPWT) is a novel form of treatment that uses subatmospheric pressure (vacuum) to effect early wound healing. [9][10][11][12][13][14][15][16] Its efficacy in reducing infections in open fractures has not been conclusively established. We aim to elucidate the effect of this therapy with respect to incidence of deep infections in open diaphyseal tibial fracture in this prospective randomized study.…”

Section: Introductionmentioning

confidence: 99%

Impact of negative pressure wound therapy on open diaphyseal tibial fractures: A prospective randomized trial

Virani¹,

Dahapute²,

Bava³

et al. 2016

Journal of Clinical Orthopaedics and Trauma

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Section: Introductionmentioning

confidence: 99%

Impact of negative pressure wound therapy on open diaphyseal tibial fractures: A prospective randomized trial

Virani¹,

Dahapute²,

Bava³

et al. 2016

Journal of Clinical Orthopaedics and Trauma

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“…Sequential irrigation and debridement coupled with the use of NPWT as a temporary wound dressing helped facilitate wound healing in a clean environment [11]. Prior to NPWT application, it is important to ensure that hemostasis within the wound bed is secured.…”

Section: Discussionmentioning

confidence: 99%

A Case Report of Traumatic Perineal Degloving Injury

Lau¹,

Lim²,

Chen³

et al. 2017

Surgery Curr Res

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Introduction: Degloving injuries are most commonly caused by road traffic accidents and industrial accidents. They result from of a large rotational force, which avulses the skin and subcutaneous tissue from the underlying fascia. The majority of such injuries involve the lower extremities. Perineal degloving injury is seldom reported in the literature. Presentation of case:In this case report, we present the case of a 22 year old male pedestrian involved in a motor vehicle accident. He sustained an open perineal degloving injury.

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“…[1][2][3][4][5][6][7] Contraindications and Precautions for VAC Therapy. [8][9][10][11][12][13][14][15][16][17][18]  Fistula to organs/body cavities  Dry eschar  Untreated osteomyelitis  Malignancy in wounds  Exposed blood vessels or organs  Long-term anticoagulant therapy  Haemophilia  Haemoglobinopathies, i.e. sickle cell disease.…”

Section: Vac Therapy Indicationmentioning

confidence: 99%

A Prospective Randomized Trial of Vacuum-Assisted Closure Versus Standard Therapy of Chronic Non-Healing Wounds

Raghupathy¹,

Sabrena²,

Vaithiswaran³

et al. 2016

jemds

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BACKGROUNDThe application of controlled levels of negative pressure has been shown to accelerate debridement and promote healing in many different types of wounds. The optimum level of negative pressure appears to be around 125 mmHg below ambient and there is evidence that this is most effective if applied in a cyclical fashion of five minutes on and two minutes off. It is believed that the negative pressure assists with removal of interstitial fluid, decreasing localised oedema and increasing blood flow. This in turn de creases tissue bacterial levels. Additionally, mechanical deformation of cells is thought to result in protein and matrix molecule synthesis, which increases the rate of cell proliferation. Despite the significant costs involved, the technique is said to compare favourably in financial terms with conventional treatments in the management of difficult to heal wounds.

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Vacuum-Assisted Closure in the Treatment of Degloving Injuries

Cited by 97 publications

References 0 publications

Impact of negative pressure wound therapy on open diaphyseal tibial fractures: A prospective randomized trial

Impact of negative pressure wound therapy on open diaphyseal tibial fractures: A prospective randomized trial

A Case Report of Traumatic Perineal Degloving Injury

A Prospective Randomized Trial of Vacuum-Assisted Closure Versus Standard Therapy of Chronic Non-Healing Wounds

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