Vacuum Assisted Closure Device Improves the Take of Mesh Grafts in Chronic Leg Ulcer Patients

Körber, Andreas; Franckson, Tom; Grabbe, Stephan; Dissemond, Joachim

doi:10.1159/000112937

Cited by 68 publications

(60 citation statements)

References 41 publications

(20 reference statements)

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“…The results of study performed by Korber et al revealed complete healing in 92.9% of meshed grafts in which they had applied VAC compared to 67.4% in the control group without postoperative VAC therapy. 20 Similar improvement was reported by Vuerstaek. 14 In our study, we used polyester tulle, impregnated with neutral triglycerides and silver ions as a primary dressing for skin grafts.…”

Section: Discussionsupporting

confidence: 81%

Management of large chronic venous leg ulcers with negative pressure wound therapy

Walczak

Wojtyniak

Jaguścik

et al. 2017

NPWTJ

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Abstract-Introduction: Venous leg ulcers (VLU) occur in 1% of the adult population and are associated with chronic disability, diminished quality of life and high health-care costs. Treatment is often slow, difficult and recurrence is high because of inappropriate conditions of the wound bed.Patients and Methods: This study involves 14 patients with chronic venous ulcers larger than 100 cm 2 treated with negative pressure wound therapy (NPWT). Patients underwent a radical debridement of all devitalized tissues and partial stripping of an insufficient great saphenous vein in the first operation. After adequate haemostasis, NPWT kit was applied. Once the wounds were determined to be clean and adequate granulation tissue formation was achieved, split-thickness skin grafts were applied. Dressing impregnated with neutral triglycerides and silver ions was used as a first layer and the black polyurethane NPWT foam was applied over it. The pain assessment was performed for 7 patients using 10 cm visual analog scale (VAS).Results: The mean number of NPWT dressing changes prior to grafting was 5.8. The mean number of NPWT foam changes was 2.8 after skin grafting. We accomplished complete healing of 92% of applied skin grafts surface. One patient had recurrence of venous ulcers in the follow-up period. Moreover, one patient required regrafting.Conclusions: The application of NPWT provides quick wound-bed preparation and high graft take in venous ulcer treatment.

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Section: Discussionsupporting

confidence: 81%

Management of large chronic venous leg ulcers with negative pressure wound therapy

Walczak

Wojtyniak

Jaguścik

et al. 2017

NPWTJ

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“…Aktuell schwierig an diesem Szenario ist allerdings die Verfügbarkeit dieser Materialien, da die Sheets mit autologen kultivierten Fibroblasten und Keratinozyten hergestellt werden. Dies bedingt Produktionszeiten von etwa 3 Wochen, was lediglich bei planbaren Eingriffen akzeptabel ist, hingegen nicht bei dem typischen dermatochirurgischen Patienten, der nach Resektion seines malignen Tumors kurzfristig versorgt werden muss [10]. Problematisch bleibt unter den aktuellen Finanzbedingungen auch die ökono-mische Abbildung, da diese High-TechProdukte mit erheblichen Kosten einhergehen.…”

Section: » Trotz Hoher Kosten Ist Der Einsatz Von Dermisersatzmateriaunclassified

Dermatochirurgie am Capillitium

Koenen¹,

Kunte

2014

Hautarzt

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Soft tissue defects of the scalp can be closed with varying techniques depending on size and depth of the defect. While small and superficial defects can be closed primarily or be left open for secondary intention healing, larger and deeper defects may need flaps or skin grafts. Extensive defects may require combined flaps or vacuum assisted closure techniques. Defects of the periosteum with denuded skull bone must be treated immediately to avoid bony complications. Usually, the tabula externa is fenestrated with holes or abraded totally to create better healing conditions. Granulation tissue may be induced on the properly prepared skull with vacuum-assisted closure, by using collagen sheets or with dermal skin substitutes. New developments in tissue engineering will surely provide new techniques for dealing with deep and extensive soft tissue defects.

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“…Meist wird die Vakuumtherapie in der Phase der Epithelisation jedoch für die Fixierung von Spalthauttransplantaten eingesetzt. Es konnte wissenschaftlich belegt werden, dass durch den Einsatz der Vakuumtherapie deren Einheilrate bei Patienten mit einem Ulcus cruris venosum signifikant höher ist [14].…”

Section: Wunden In Der Dermatologieunclassified

“…Meist wird empfohlen, den Sog während der Vakuumtherapie für die Fixierung von Spalthauttransplantaten auf 75 mmHg zu reduzieren. In eigenen Untersuchungen haben wir jedoch auch einen Sog von 125 mmHg erfolgreich eingesetzt [14]. Für die Fixierung der Spalthauttransplantate wird meist der PVA-Schwamm verwendet, da er aufgrund der Oberflächenstruktur direkt auf die Spalthaut appliziert werden kann.…”

Section: Wunden In Der Dermatologieunclassified

Vakuumtherapie chronischer Wunden in der Dermatologie

Dissemond

2008

Hautarzt

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Although the positive effects of negative pressure-therapy in wound-healing has been well known for several decades, the first paper on the now widely used vacuum systems was published ten years ago. Since then vacuum-therapy has been widely used in patients with"hard-to-heal" wounds, including dermatologic patients. Although there is still a lack of relevant comparative prospective controlled clinical trials, vacuum-therapy seems to accelerate the healing process in chronic wounds in both the granulation and epithelialization phases. Therefore, following debridement, vacuum-therapy can be considered as the therapy of choice for many patients with chronic wounds.

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Vacuum Assisted Closure Device Improves the Take of Mesh Grafts in Chronic Leg Ulcer Patients

Cited by 68 publications

References 41 publications

Management of large chronic venous leg ulcers with negative pressure wound therapy

Management of large chronic venous leg ulcers with negative pressure wound therapy

Dermatochirurgie am Capillitium

Vakuumtherapie chronischer Wunden in der Dermatologie

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