Vaccine Hesitancy among European Parents—Psychological and Social Factors Influencing the Decision to Vaccinate against HPV: A Systematic Review and Meta-Analysis

Abstract

Background: Due to low adherence to HPV vaccination programs, the European region struggles with vaccination rates lower than 30% among the targeted population. The present report investigated various socio-demographic and psychological factors influencing European parents’ hesitancy towards vaccinating their children. Methods: As of September 2023, four databases were searched. After applying inclusion criteria, all articles comparing psychological and socio-demographic factors in parents who vaccinate or do not vaccinate their children were included. Results: Twenty-five primary publications met the criteria, totaling 385,460 responders, of which 311,803 want to or have already vaccinated their child, and 73,555 do not wish to do so. Immigrant and employment status, religion, age of parents and the child’s gender seemed to influence their decision to vaccinate their child. Previous experience with vaccines, perceived safety and efficacy and the mother’s previous abnormal CCS results also impacted their decision. The caregivers’ education, gender, civil status, number of children, family history of neoplasia or mother’s CCS attendance did not influence their hesitancy to vaccine. Conclusion: Multiple demographic, social, economic and psychological barriers involved in the parents’ hesitancy to vaccinate their children against the HPV virus were highlighted. Specific at-risk categories that need to be targeted with information, education and vaccination campaigns were identified.

Screening for High-Risk Human Papillomavirus Reveals HPV52 and HPV58 among Pediatric and Adult Patient Saliva Samples

“…This information is also important to oral healthcare and public health professionals, as recent evidence has demonstrated that vaccine hesitancy (particularly related to HPV among pediatric patients) has been increasing in recent years despite strong evidence for the efficacy and safety of both the quadrivalent and nine-valent HPV vaccines [ 38 , 39 , 40 ]. In fact, other recent evidence has also documented the increase in vaccine hesitancy and skepticism about vaccine safety and efficacy over recent years among children, adolescents, and their parents [ 41 , 42 ]. One of the most effective and important methods for addressing vaccine hesitancy may be current information regarding HPV prevalence and infections among the patient population, such as that presented in this study, which demonstrates the relevance and importance of vaccination against high-risk oral HPV strains even in very young patients [ 43 , 44 , 45 ].…”