Vaccine Confidence and Hesitancy at the Start of COVID-19 Vaccine Deployment in the UK: An Embedded Mixed-Methods Study

Brindle, Hannah; Rogers, Nina Trivedy; Eggo, Rosalind M; Enria, Luisa; Lees, Shelley

doi:10.3389/fpubh.2021.745630

Cited by 35 publications

(36 citation statements)

References 40 publications

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“…These perceptions are at odds with the official government communication that recommends vaccines. Low trust in government has been reported to be associated with COVID-19 vaccine rejection [ 31 ]. Public health risk communication messages must convey accurate and objective knowledge and understanding of risks and hazards that affect health to diverse audiences [ 4 ].…”

Section: Discussionmentioning

confidence: 99%

Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan

et al. 2022

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Understanding vaccine hesitancy, considering the target region and phase, is an urgent issue to quell the coronavirus disease (COVID-19) pandemic. This study aimed to monitor COVID-19 vaccine hesitancy in the Japanese population during the three phases of vaccine approval and introduction, and evaluate the association of vaccine hesitancy with vaccine confidence and literacy. We conducted web-based cross-sectional surveys during the three phases of COVID-19 vaccine introduction: January 2021, before approval; June, start of vaccination of the elderly; and September, when about 70% of the target population was vaccinated with at least one dose. There were 7210 participants, aged 20–80 years. We evaluated the association of vaccine hesitancy with vaccine confidence and literacy in the three phases using multivariate logistic regression analysis. The proportion of hesitancy in January, June, and September was 17.5%, 65.3%, and 19.4%, respectively. In any phase, lower vaccine confidence and literacy showed a higher adjusted odds ratio (AOR) of vaccine hesitancy in most items (AOR > 1, p < 0.001). Vaccine hesitancy in June had a different trend in perception of COVID-19 compared to that in the January and September surveys. The findings suggested that hesitancy increases transiently during vaccination introduction phases, and changes as the vaccination program progressed or waves of epidemic. Careful risk communication to increase vaccine confidence and literacy is essential to reduce vaccine hesitancy, especially in the introduction phase.

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Section: Discussionmentioning

confidence: 99%

Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan

et al. 2022

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“…The COVID-19 pandemic caused a major global health, social, and economic crisis. At the end of December 2020, the approval of the first vaccine started the global vaccination program, which restored minimal confidence in the population [ 97 ]. The scientific community is convinced that, without a broad and comprehensive vaccination program, it will be impossible to overcome COVID-19.…”

Section: The Scovid-19 Pandemic and Its Impact On Forensic Investigat...mentioning

confidence: 99%

The Impact of the COVID-19 Pandemic on the Practice of Forensic Medicine: An Overview

et al. 2022

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During the COVID-19 pandemic, forensic sciences, on the one hand, contributed to gaining knowledge about different aspects of the pandemic, while on the other hand, forensic professionals were called on to quickly adapt their activities to respond adequately to the changes imposed by the pandemic. This review aims to clarify the state of the art in forensic medicine at the time of COVID-19, discussing the following: the influence of external factors on forensic activities, the impact of autopsy practice on COVID-19 and vice-versa, the persistence of SARS-CoV-2 RNA in post-mortem samples, forensic personnel activities during the SARS-CoV-2 pandemic, the global vaccination program and forensic sciences, forensic undergraduate education during and after the imposed COVID-19 lockdown, and the medico-legal implications in medical malpractice claims during the COVID-19 pandemic. The COVID-19 pandemic has greatly influenced different aspects of human life, and, accordingly, the practical activities of forensic sciences that are defined as multidisciplinary, involving different expertise. Indeed, the activities are very different, including crime scene investigation (CSI), external examination, autopsy, and genetic and toxicological examinations of tissues and/or biological fluids. At the same time, forensic professionals may have direct contact with subjects in life, such as in the case of abuse victims (in some cases involving children), collecting biological samples from suspects, or visiting subjects in the case of physical examinations. In this scenario, forensic professionals are called on to implement methods to prevent the SARS-CoV-2 infection risk, wearing adequate PPE, and working in environments with a reduced risk of infection. Consequently, in the pandemic era, the costs involved for forensic sciences were substantially increased.

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“…In their study of psychological factors associated with COVID-19 vaccine hesitancy and resistance in Ireland and the United Kingdom, Murphy et al (2021) found that those who were vaccine hesitant, as well as those who were resistant, were more self-serving, held strong religious viewpoints, and held an internal locus of control. Another study from the U.K. that provided examples of other contributors, cited mistrust in politicians and science ( Roberts et al, 2021 ). Additional factors to vaccine hesitancy, particularly in the U.S., included vaccine safety, vaccine effectiveness, anxiety over potential side effects, and mistrust of the healthcare system and government ( Khubchandani et al, 2021 ; Pogue et al, 2020 ).…”

Section: Introductionmentioning

confidence: 99%

Exploring vaccine hesitancy determinants during the COVID-19 pandemic: An in-depth interview study

Morales

Lee

Bradford

et al. 2022

SSM - Qualitative Research in Health

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On January 20, 2020, the CDC reported its first case of the novel coronavirus in the United States. Almost a year and a half later, efforts to vaccinate individuals in the hopes of achieving herd immunity continue. Despite the amounts of scientific breakthroughs to create and disseminate the vaccines, people continue to express hesitancy. Existing research has explored vaccine hesitancy through survey data, restricting an in-depth understanding for why people remain hesitant. As a result, this research aimed to understand in-depth reasons for vaccine hesitancy as well as what finally got those who, although hesitant, went through with getting inoculated. In addition, we also wanted to know how the vaccine hesitant received information about the vaccine. Using in-depth interviews, we identified key elements that influenced vaccine hesitancy which include social pressure to not get vaccinated and lack of trust in the healthcare system. We also identified reasons why vaccine hesitant individuals ultimately decided to receive the COVID-19 vaccine. These reasons included becoming informed, getting back to normal, and societal pressure. Finally, we sought to understand what served as venues for COVID-19 information and those were media sources like traditional news outlets/legacy media (e.g., TV) and digital/social media, and interpersonal sources like family, friends, and co-workers. In revealing these factors through in-depth interviews, we show how complex vaccine hesitancy is and the elements public health practitioners need to take into consideration when constructing vaccine-related information/messages.

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Vaccine Confidence and Hesitancy at the Start of COVID-19 Vaccine Deployment in the UK: An Embedded Mixed-Methods Study

Cited by 35 publications

References 40 publications

Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan

Association of Vaccine Confidence and Hesitancy in Three Phases of COVID-19 Vaccine Approval and Introduction in Japan

The Impact of the COVID-19 Pandemic on the Practice of Forensic Medicine: An Overview

Exploring vaccine hesitancy determinants during the COVID-19 pandemic: An in-depth interview study

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