Vaccine co-administration in adults: An effective way to improve vaccination coverage

Bonanni, Paolo; Steffen, Robert; Schelling, Jörg; Balaisyte-Jazone, Lina; Posiuniene, Inga; Zatoński, Maciej; Damme, Pierre Van

doi:10.1080/21645515.2023.2195786

Cited by 26 publications

(23 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Technical and scientific valuable documents are also essential, capable of promoting professionals training and homogenous behaviors adoption based on the best scientific evidence. 30 , 31 All this, however, will not be possible without a rapid and integral impulse to computerize and digitalize vaccination registries to ensure vaccination coverage real-time updating and maximum interoperability of the vaccine information. Notably, most of these good practices have been listed as essential objectives in the current National Vaccination Plan.…”

Section: Discussionmentioning

confidence: 99%

Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy

Poscia,

Paolorossi,

Collamati

et al. 2024

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

Infectious diseases pose a significant burden on the general population, particularly older adults who are more susceptible to severe complications. Immunization plays a crucial role in preventing infections and securing a healthier aging, but actual vaccination rates among older adults and frail individuals (OAFs) remains far from recommended targets. This study aims to collect and share good practices implemented in several Italian local health districts during the SARS-CoV-2 pandemic to ease routine immunization for OAFs. A 28-items questionnaire has been developed to collect information on organization aspect of immunization services and local good practices implemented before and during the SARS-CoV-2 pandemic. Twelve Public Health managers representative of 9 Italian Regions were further interviewed between January and March 2021. Despite literature suggests several effective interventions to increase vaccine demand, improve vaccine access, and enhance healthcare providers’ performance, our survey highlighted substantial heterogeneity in their implementation at local level. Seven good local practices have been identified and described: mass vaccination centers; vaccination mobile units; drive-through vaccination; co-administration; tailored pathways; cooperation among providers involved in vaccination; digitization. Our survey pointed out valuable strategies for enhancing routine immunization for OAFs. Providers should combine effective interventions adequate to their specific context and share good practices.

show abstract

Section: Discussionmentioning

confidence: 99%

Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy

Poscia,

Paolorossi,

Collamati

et al. 2024

Human Vaccines & Immunotherapeutics

View full text Add to dashboard Cite

show abstract

“…Though coadministration of pneumococcal vaccine with COVID-19 vaccines would be desirable to improve vaccination coverage, published data on immunologic interference are not available [ 73 ]. Such data should gradually be available, given a preliminary report from a Phase III randomized trial (ClinicalTrials.gov Identifier NCT04887948, last updated 14 December 2022) supporting the safety and immunogenicity of PCV20 co-administered with a booster dose of mRNA COVID-19 vaccine.…”

Section: Coadministration Of Pneumococcal Vaccine With Other Vaccinesmentioning

confidence: 99%

Pneumococcal Vaccination in Adults: A Narrative Review of Considerations for Individualized Decision-Making

See

2023

Vaccines

View full text Add to dashboard Cite

Pneumococcal disease remains one of the major causes of severe disease in both children and adults. Severe disease may be prevented by pneumococcal polysaccharide and conjugate vaccines, which currently cover more than 20 serotypes. However, unlike routine pneumococcal vaccination in children, guidelines promote only limited pneumococcal vaccination in adults, and do not cater for decision-making for individual patients. In this narrative review, considerations for individualized decision-making are identified and discussed. This review identifies and discusses considerations for individualized decision-making, including the risk of severe disease, immunogenicity, clinical efficacy, mucosal immunity, herd immunity, concomitant administration with other vaccines, waning immunity, and replacement strains.

show abstract

“…Vaccine co-administration describes the process in which two or more vaccines are administered during the same appointment or session. Vaccine co-administration has been identified as a useful strategy to improve vaccine coverage rates and compliance with national immunization programs (NIPs) by reducing the number of vaccination sessions needed, 1 , 2 thereby reducing the resource utilization of vaccination services in addition to potential stress imposed on children and parents. 2–4 Furthermore, co-administration may also reduce the number of missed opportunities for vaccination, a key contributor to incomplete immunization.…”

Section: Introductionmentioning

confidence: 99%

“… 2–4 Furthermore, co-administration may also reduce the number of missed opportunities for vaccination, a key contributor to incomplete immunization. 2 , 5 …”

Section: Introductionmentioning

confidence: 99%

“…Although the impact on immunogenicity must be considered when co-administering vaccines, the combination of pediatric vaccines typically has no significant impact on immunogenicity profiles, and is seen as common practice in many countries. 2 A survey conducted in Calabria, Italy, in 2022, reported that the majority of healthcare professionals (HCPs) supported vaccine co-administration as an effective strategy to improve immunization calendars, as it can provide a range of benefits to healthcare systems and patients. 15 However, concerns were raised regarding the lack of readily available information on the safety of concomitant administration of multiple vaccines in pediatric populations, which could limit the implementation of coadministration strategies.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals

Bonanni,

Castagna,

Gabutti

et al. 2024

Human Vaccines & Immunotherapeutics

Self Cite

View full text Add to dashboard Cite

Vaccine co-administration is a useful strategy for improving vaccine coverage and adherence. In Italy, an update to the national immunization program (NIP) in 2023 included recommendations for co-administration of pediatric vaccines, including the four-component vaccine for meningococcus B (4CMenB), pneumococcal conjugate vaccine (PCV), hexavalent vaccines, and oral rotavirus vaccines. Safety is a major concern when considering vaccine co-administration; therefore, a literature review of the available evidence on 4CMenB co-administration with PCV, hexavalent/pentavalent, and rotavirus vaccines was performed. Of 763 publications screened, two studies were reviewed that reported safety data on 4CMenB co-administration with PCV, hexavalent/pentavalent, and rotavirus vaccines in infants aged 0–24 months. Overall, these studies supported that there were no significant safety signals when co-administering 4CMenB with PCV, hexavalent/pentavalent, and rotavirus vaccines, compared with individual vaccination. This review provides key insights for healthcare professionals on the tolerability of co-administering 4CMenB with routine vaccines.

show abstract

Vaccine co-administration in adults: An effective way to improve vaccination coverage

Cited by 26 publications

References 41 publications

Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy

Enhancing routine immunization efforts for older adults and frail individuals: Good practices during the SARS-CoV-2 pandemic in Italy

Pneumococcal Vaccination in Adults: A Narrative Review of Considerations for Individualized Decision-Making

Available evidence on the co-administration of the four-component meningococcal B vaccine (4CMenB) with three vaccines at the same visit among pediatric individuals

Contact Info

Product

Resources

About