Vaccine-Associated Anaphylactic Shock in a Springer Spaniel Dog with Arrhythmogenic Right Ventricular Cardiomyopathy

Bertola, Luca; Cappelleri, Andrea; Tomba, Raffaella MA.; Dotti, Elisa; Caniatti, M.; Dall’Ara, P.; Recordati, Camilla

doi:10.1016/j.jcpa.2022.03.009

Cited by 2 publications

(1 citation statement)

References 18 publications

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“…Además, se debe descartar una posible reacción de hipersensibilidad tipo I u otras reacciones adversas; en caso de anafilaxia severa tratar con epinefrina en dilución 1:1,000 (1 mg/mL) a 0.01 mg/kg vía intramuscular (IM) (máxima dosis 0.3 mg en pacientes < 40 kg y 0.5 mg en pacientes > 40 kg). Seguidamente (5 minutos) infusión a velocidad constante a 0.05 µg/min/kg IV (38,39).…”

Section: Terapéutica De La Ofidiotoxicosis En Caninosunclassified

Clinical protocol for the care of ophidiotoxicosis in canines in Colombia

Herrera-Dalel,

Montoya-Forero,

Zambrano-Lugo

et al. 2024

Rev MVZ Córdoba

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Every year, according to the World Health Organization, nearly 5,000,000 million accidents due to snake bites are reported worldwide, of which it is estimated that 33.3% to 50% of cases present as poisoning. Ophidic accidents that include ophidiotoxicosis have care protocols of therapy with antivenom serums, which vary according to the genus and species of the snake. Although in Colombia there are protocols for the care of ophidiotoxicosis in humans described by health entities, the canine clinic lacks this information. The aim of this systematic review is to build a medical protocol for ophidiotoxicosis in canines based on information reported in Colombia or tropical countries with which similar venomous snakes are shared. For this action, the PRISMA protocol was used; in total, 57 articles and 10 official documents on protocols for the care of ophidic accidents in humans were reviewed, which allowed the possible to classify snakebite accidents in group 1 (Bothrops, Lachesis and Crotalus accidents) and group 2 (Micrurus accident), also establish a medical protocol for ophidiotoxicosis in each of the groups indicated in canines, depending on the severity of the clinical and paraclinical condition. In conclusion, the clinical and paraclinical signs of the canine, vasculotoxic or neurotoxic, allow us to identify the group to which the aggressor snake belongs (group 1 or group 2, respectively), and their severity guides the selection and dosage of antivenom therapy specific for the clinical management of ophidiotoxicosis in canines.

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Section: Terapéutica De La Ofidiotoxicosis En Caninosunclassified

Clinical protocol for the care of ophidiotoxicosis in canines in Colombia

Herrera-Dalel,

Montoya-Forero,

Zambrano-Lugo

et al. 2024

Rev MVZ Córdoba

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In Vivo Approaches to Understand Arrhythmogenic Cardiomyopathy: Perspectives on Animal Models

Risato,

Brañas Casas,

Cason

et al. 2024

Cells

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Arrhythmogenic cardiomyopathy (AC) is a hereditary cardiac disorder characterized by the gradual replacement of cardiomyocytes with fibrous and adipose tissue, leading to ventricular wall thinning, chamber dilation, arrhythmias, and sudden cardiac death. Despite advances in treatment, disease management remains challenging. Animal models, particularly mice and zebrafish, have become invaluable tools for understanding AC’s pathophysiology and testing potential therapies. Mice models, although useful for scientific research, cannot fully replicate the complexity of the human AC. However, they have provided valuable insights into gene involvement, signalling pathways, and disease progression. Zebrafish offer a promising alternative to mammalian models, despite the phylogenetic distance, due to their economic and genetic advantages. By combining animal models with in vitro studies, researchers can comprehensively understand AC, paving the way for more effective treatments and interventions for patients and improving their quality of life and prognosis.

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Vaccine-Associated Anaphylactic Shock in a Springer Spaniel Dog with Arrhythmogenic Right Ventricular Cardiomyopathy

Cited by 2 publications

References 18 publications

Clinical protocol for the care of ophidiotoxicosis in canines in Colombia

Clinical protocol for the care of ophidiotoxicosis in canines in Colombia

In Vivo Approaches to Understand Arrhythmogenic Cardiomyopathy: Perspectives on Animal Models

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