Vaccine against Jembrana Disease Virus Infection: A Summary Findings

Abstract

Jembrana disease constitutes the main concern in cattle industry especially in Indonesia and Australia as it has caused important economic losses due to mortality of cattle. The pathology of the disease is unusual for a lentivirus infection as it is associated with a severe, often lethal disease syndrome and a short incubation period in cattle. For lack of efficient medical treatment of JDV-infected cattle, vaccination may therefore constitute an effective measure for the prevention or eradication of Jembrana disease. Up to date, only one type of vaccine has been reported and tested. It is based on inactivated, tissue-derived virus antigens (Tabanan/87 isolate, JDV TAB/87 ). This review summarize show current Jembrana disease vaccine was developed as well as evaluated and how these information might be useful in future vaccine design.

Potential of polylactic-co-glycolic acid (PLGA) for delivery Jembrana disease DNA vaccine Model (pEGFP-C1-tat)

“…Bali cattle are considered one of Indonesia's superior livestock types. However, the Bali cattle's main weakness is their susceptibility to Jembrana disease [ 1 ], which is caused by the Jembrana disease virus (JDV) [ 2 ]. Economic losses caused by Jembrana disease are significant, taking the form of death of 5,000 Bali cattle in one year in the first JDV outbreak in Indonesia and affecting the distribution of Bali cattle between islands [ 3 ].…”