Vaccinations in children with cancer

Esposito, Susanna; Cecinati, Valerio; Brescia, Letizia Pomponia; Principi, Nicola

doi:10.1016/j.vaccine.2010.02.096

Cited by 43 publications

(53 citation statements)

References 69 publications

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“…It is also well known that steroid therapy does not contraindicate vaccination except when high doses are used: in such cases, it is better to postpone the vaccination if possible -not for safety reasons but in order to ensure adequate immunogenicity [35].…”

Section: Discussionmentioning

confidence: 99%

Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents

Esposito

Azzari

Bartolozzi

et al. 2010

Vaccine

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a b s t r a c tA cross-sectional survey of Italian pediatricians and pediatric residents was carried out between 15 September and 18 October 2008 in order to evaluate their knowledge concerning the administration of vaccines to children with suspected or proved allergies. Of the 750 physicians who accepted to participate (620 pediatricians and 130 residents), 630 (84.0%; 407 females; mean age 43.5 ± 11.2 years) returned completed questionnaires: 268 primary care pediatricians (42.5%), 244 hospital pediatricians (38.8%), and 118 pediatric residents (18.7%). Knowledge concerning the vaccination of children with suspected or proved allergies was far from optimal, with the poorest knowledge being shown by the pediatric residents and no difference between the primary care and hospital pediatricians. Since pediatricians are the main parents' advisors regarding vaccinations, these results indicate an urgent need for educational programmes (especially for residents) and evidence-based guidelines concerning vaccinations in children with suspected or proved allergies.

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Section: Discussionmentioning

confidence: 99%

Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents

Esposito

Azzari

Bartolozzi

et al. 2010

Vaccine

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“…Accepted for publication Sep 8, 2014 contribute to poorer overall and event-free survival. 1,6 In addition, from an infection prevention standpoint, immunization may also reduce risk of transmission among high-risk patients with more outpatient visits and inpatient admissions.…”

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confidence: 99%

Quality Improvement Initiative to Increase Influenza Vaccination in Pediatric Cancer Patients

Freedman¹,

Reilly

Powell

et al. 2015

Pediatrics

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BACKGROUND: Pediatric patients with cancer face more severe complications of influenza than healthy children. Although Centers for Disease Control and Prevention guidelines recommend yearly vaccination in these patients, in our large academic center, ,60% of oncology patients receiving chemotherapy were immunized at baseline. Our objective was to increase this rate through a multifaceted quality improvement initiative.METHODS: Eligible patients were .6 months old, within 1 year of receiving chemotherapy, .100 days from stem cell transplant, and had $1 outpatient oncology visit between September 1, 2012, and March 31, 2013. Five interventions were instituted concomitantly: (1) family education: influenza/ vaccine handouts were provided to families in clinic waiting rooms; (2) health informatics: daily lists of outpatients due for immunization were generated from the electronic medical record and sent automatically to triage staff and nurses; (3) outpatient clinic: patients due for vaccination were given colored wristbands during triage to alert providers; (4) inpatient: vaccine order was built into admission order set; and (5) provider education: staff education was provided at conferences on screening of patients, vaccine ordering, and documentation of refusals/contraindications. RESULTS:The complete influenza immunization rate increased by 20.1% to 64.5%, and the proportion of patients receiving $1 dose of vaccination increased by 22.9% to 77.7%. Similar changes were noted across all cancer types, with highest rates of immunization in leukemia/lymphoma patients (86.8%) and lowest in patients after stem cell transplant (66.7%).CONCLUSIONS: Technology, education, and multidisciplinary clinical process changes increased influenza vaccination rates. Ongoing efforts are targeting subgroups with lowest rates of immunization.

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“…The dTp is recommended for: 103,106,107 (i) all patients 6 months after HSCT (a 3-dose series of a vaccine with high tetanus and acellular pertussis content [DTaP] may be more immunogenic and should be considered for the initial vaccination, regardless of patient age, whereas dTap should be used as a booster rather than as part of the primary series); (ii) 3 months after cancer chemotherapy, patients should be vaccinated with dTap, and in regimens that include anti-B-cell antibodies, vaccination should be delayed at least 6 months; (iii) patients with chronic inflammatory illness who are in treatment with immunosuppressive drugs; (iv) HIV-infected patients, based upon their serological status; and (v) SOT candidates or end-stage heart, kidney, liver and lung disease, based upon their serological status.…”

Section: Diphtheria Tetanus Pertussis (Dtp) Vaccinationmentioning

confidence: 99%

Recommended immunization schedules for adults: Clinical practice guidelines by the Escmid Vaccine Study Group (EVASG), European Geriatric Medicine Society (EUGMS) and the World Association for Infectious Diseases and Immunological Disorders (WAidid)

Esposito

Bonanni

Maggi

et al. 2016

Human Vaccines & Immunotherapeutics

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Rapid population aging has become a major challenge in the industrialized world and progressive aging is a key reason for making improvement in vaccination a cornerstone of public health strategy. An increase in age-related disorders and conditions is likely to be seen in the near future, and these are risk factors for the occurrence of a number of vaccine-preventable diseases. An improvement in infectious diseases prevention specifically aimed at adults and the elderly can therefore also decrease the burden of these chronic conditions by reducing morbidity, disability, hospital admissions, health costs, mortality rates and, perhaps most importantly, by improving the quality of life. Among adults, it is necessary to identify groups at increased risk of vaccine-preventable diseases and highlight the epidemiological impact and benefits of vaccinations using an evidence-based approach. This document provides clinical practice guidance on immunization for adults in order to provide recommendations for decision makers and healthcare workers in Europe. Although immunization is considered one of the most impactful and cost-effective public health measures that can be undertaken, vaccination coverage rates among adults are largely lower than the stated goal of 95% among adults, and stronger efforts are needed to increase coverage in this population. Active surveillance of adult vaccine-preventable diseases, determining the effectiveness of the vaccines approved for marketing in the last 5 y, the efficacy and safety of vaccines in immunocompromised patients, as well as in pregnant women, represent the priorities for future research.

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Vaccinations in children with cancer

Cited by 43 publications

References 69 publications

Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents

Knowledge of vaccination of allergic children among Italian primary care pediatricians, hospital pediatricians and pediatric residents

Quality Improvement Initiative to Increase Influenza Vaccination in Pediatric Cancer Patients

Recommended immunization schedules for adults: Clinical practice guidelines by the Escmid Vaccine Study Group (EVASG), European Geriatric Medicine Society (EUGMS) and the World Association for Infectious Diseases and Immunological Disorders (WAidid)

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