Vaccination and Autoimmune Phenomena

Kamińska

Journal of Health Study and Medicine

et al. 2023

Borrelia burgdorferi sensu lato is a Gram-negative spirochete that causes Lyme disease (Lyme borreliosis). The signs and symptoms of Lyme disease are a consequence of the immune response to spirochete in soft tissues, and it is debated if said immune response can become an autoimmune disease of the body over time due to bacterial and HLA/MHC molecular mimicry. Continual Lyme Disease (CDL) also known as Post-Treatment Lyme Disease Syndrome (PTLDS) is a broad group of rapidly appearing flu-rash symptoms and cognitive difficulties combined with chronic fatigue that is observed after at least six months after completing treatment. This review contains scientific collections throughout the last 10 years of studies related to alleged post-infection auto-immunogenicity.

Section: Introductionmentioning

confidence: 90%

Borrelia Burgdorferi Sensu Lato Infection-induced Autoimmunity – A Decennary Literature Review

Kamińska

Journal of Health Study and Medicine

et al. 2023

RNA vaccines: A milestone toward a new era

Jankovic

2023

VOJNOSANIT PREGL

Childhood vaccination in the twenty-first century: Parental concerns and challenges for physicians

Janković¹

2019

Arhiv za farmaciju

Vaccination is one of the most important methods of prevention of infectious disease, saving millions of lives worldwide and protecting people from potentially debilitating complications. It is therefore hailed as one of the greatest advances of science-based medicine of all times. Although repeatedly proven safe and effective, vaccination has been questioned and resented throughout its long history. Vaccine hesitancy and refusal are once again on the rise in this century, due to a complex interplay of numerous factors and circumstances. A decline in childhood vaccination rates has already resulted in resurgence of hitherto eliminated vaccinepreventable diseases in many countries, and is now perceived as a major public health threat. This decline is closely related to increasing spread of misinformation regarding vaccine safety and effectiveness, coupled with a growing anti-vaccine activism. This, among other issues, underscores the need to improve communication between healthcare workers and parents, as well as devise a more comprehensive approach to boosting vaccine confidence, where scientists, physicians, media and the general public all have important roles to play. In this paper, we discuss the phenomenology and causal structure of vaccine hesitancy and refusal, and briefly review some widespread vaccine-related questions of everyday practical importance.