Vaccination Against Rotavirus  Infection:  10-Year Global Experience  of Successful Use

Намазова-баранова, Л. С.; Федосеенко, М. В.; Вишнева, Е.А.; Таточенко, В. К.; Selimzyanova, L.R.; Чемакина, Д. С.

doi:10.15690/vsp.v16i4.1773

Cited by 7 publications

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References 42 publications

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“…К 2012 г. в Европе заболеваемость инвазивной Hib-инфекцией у детей в возрасте до 5 лет была спорадической и составляла, по данным Европейского центра профилактики и контроля заболеваний, 0,19 на 100 000 населения [51]. Заболеваемость инвазивными инфекциями гемофильной этиологии у детей в возрасте до 5 лет в 2016 г. в США составила 0,22 на 100 000, что ниже целевого показателя программы Healthy People 2020 (0,27 на 100 000) [52].…”

Section: вакцинация против гемофильной инфекцииunclassified

New Horizons of National Immunization Calendar

Намазова-Баранова

Федосеенко

Баранов

2019

Vopr. sovr. pediatr.

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Containment, prevention and elimination of infectious disease is the state duty for citizens. Development of the National Immunization Calendar as well as challenges in preventive vaccination system both are significant investment into the future. Advantages of vaccination are not limited only by infection diseases control. Experts of World Health Organization recognize positive influence of immunization on economic. Vaccines give unprecedented opportunities on alleviation of human sufferings but it can be possible only due to perfect work of immunization calendar. It is necessary to estimate our National Immunization Calendar alongside with suggested by World Health Organization and professional associations plans. It is essential to estimate experience and facilities of modern vaccinology. This entailed the optimal preventive vaccination schedule, which can be implemented in the structure of existing national calendar.

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Section: вакцинация против гемофильной инфекцииunclassified

New Horizons of National Immunization Calendar

Намазова-Баранова

Федосеенко

Баранов

2019

Vopr. sovr. pediatr.

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New Possibilities of Preventive Immunization for Rotavirus Infection in Russian Federation. Overview of the Innovative Rotavirus Vaccine Profile

et al. 2023

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This article is devoted to the issue of rotavirus infection in pediatric population and demonstrates worldwide prevalence of rotavirus among the causes of viral gastroenteritis and its persistent leadership among the causes of fatal diarrhea in children of the first 5 years of life. Specific prevention of rotavirus infection has been actively carried out around the world since 2005. Nowadays, we have adequate experience in the use of various rotavirus vaccines bolstered by their implementation in immunisation schedules for infants. The authors provide data on the efficacy and safety of rotavirus vaccines licensed and used in Russian Federation, involving the results of studies on safety, immunological and clinical efficacy of one of the pentavalent rotavirus vaccines.

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Genetic characteristics of group A rotaviruses circulating in the Orenburg region during various epidemic seasons

Denisyuk

2021

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Objective. To analyze the genetic structure of rotaviruses of group A, circulating on the territory of the Orenburg region in different epidemic seasons.Materials and methods: The genetic structure of rotaviruses by G/P alleles was determined in 341 fecal samples of patients with gastroenteritis clinic under the age of 5 years in various epidemic seasons. ELISA and PCR methods were used. The typing of rotaviruses was conducted on the basis of the laboratory of molecular diagnostic and epidemiology of enteric infections of the Department molecular diagnostics Central research Institute of epidemiology.Results: The general genetic structure of group a rotaviruses circulating in the Orenburg region in the period from 2014—2020 was determined, expressed, by the frequencies of G/P alleles. The genetic potential of group a rotaviruses for the entire study period was represented by twelve variants of genotypes for G/P alleles, the leading role in the epidemic process was played by genotypes with the highest frequency of occurrence: G4[P]8, G9[P]8, G2[P]4, Mixt. The frequency of registration of combined forms of various rotavirus genotypes (Mixed forms) was 5,9%.Conclusion: The main and dominant genotypes, their regional diversity and inter-seasonal fluctuations are established. The spectrum of circulating rotavirus genotypes differed in different epidemic seasons, and their epidemic significance is shown.

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Vaccination Against Rotavirus Infection: 10-Year Global Experience of Successful Use

Abstract: The article reviews the results of scientific researches published over the past few years that confirm the significant socioeconomic burden of rotavirus infection and its significant contribution to the morbidity and mortality of the world's children '

Cited by 7 publications

References 42 publications

New Horizons of National Immunization Calendar

New Horizons of National Immunization Calendar

New Possibilities of Preventive Immunization for Rotavirus Infection in Russian Federation. Overview of the Innovative Rotavirus Vaccine Profile

Genetic characteristics of group A rotaviruses circulating in the Orenburg region during various epidemic seasons

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