Vaccination against gonadotropin-releasing factor (GnRF) with Bopriva significantly decreases testicular development, serum testosterone levels and physical activity in pubertal bulls

Janett, F.; Gerig, Thomas M.; Tschuor, A; Amatayakul-Chantler, S.; Walker, John; Howard, R.; Bollwein, Heinrich; Thun, R.

doi:10.1016/j.theriogenology.2012.01.035

Cited by 55 publications

(39 citation statements)

References 39 publications

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“…Muscle pH 24 was higher in bulls than steers and immunocastrates (Miguel et al, 2014) possibly due to ante-mortem stress, as bulls are argued to be more susceptible to stress as a result of their temperament (Field,1991). This can be supported by the differences seen in activity levels between bulls and immunocastrates (Janett et al, 2012). This increase in pH seen in bulls could explain the lower L* colour values in comparison to immunocastrates.…”

Section: Cattlementioning

confidence: 75%

“…However, no differences in CIE colour values were observed by AmatayakulChantler et al (2012) and Amatayakul-Chantler et al (2013) and thus this warrants further investigation. Similarly, the effects of immunocastration on tenderness, measured by instrumental shear force, varies with those indicating it has no effect (Cook et al, 2000;Ribeiro et al, 2004;Amatayakul-Chantleret al 2013;Miguel et al, 2014) versus Amatayakul-Chantler et al (2012) who reported that immunocastrates had more tender meat than bulls. However, it is important to note that numerous factors such as the ante-mortem stress, the killing process, post-mortem interventions, and even the method used to cook the samples prior to evaluation for tenderness can influence the shear force values and thus these too require further investigation.…”

Section: Cattlementioning

confidence: 99%

“…In bulls, immunocastration, with Bopriva ® has been successful in decreasing testosterone levels to those comparable to physical castrates within 14 days after the booster (Amatayakul-Chantler et al, 2013) and thereby controlling aggressive and sexual behaviour (Huxsoll et al, 1998) as well as decreasing overall activity (Janett et al, 2012). The use of Bopriva ® in cattle has shown consistent immune responses in individuals, which is not always shown to be experienced with small-scale vaccines manufactured for research purposes (Thompson, 2000).…”

Section: Cattlementioning

confidence: 99%

“…Thus, the flexibility with regards to when immunocastration is applied can allow the manipulation of carcass traits in bulls of varying maturity types. Positive results have been experienced with regards to applying immunocastration to Bos indicus and Bos indicus crossbred cattle in both extensive and feedlot systems (Amatayakul-Chantler et al, 2012;Amatayakul-Chantler et al, 2013;Miguel et al, 2014). Immunocastrated bulls appear to have greater development in the hindquarter than steers and bulls, indicated by an increase in the leg perimeter of the hindquarter (Miguel et al, 2014) and thus a higher proportion of economically important cuts.…”

Section: Cattlementioning

confidence: 99%

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Castration of male livestock and the potential of immunocastration to improve animal we

Needham¹,

Lambrechts²,

Hoffman³

2017

SA J. An. Sci.

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Growing consumer awareness about animal welfare has led to the assessment of the impact of common farming practices, such as physical castration, on animal well-being under production conditions. Physical castration is used in livestock industries to prevent indiscriminate breeding, control aggression, and improve meat and carcass quality. In terms of animal welfare, physical castration causes pain, decreased growth performance, infection, and mortality. An alternative approach to castration is thus warranted that will ensure optimal growth without compromising the castrated animal's wellbeing. Immunocastration has proved to be an effective method of suppressing the development and functioning of the reproductive system in various domesticated and wildlife species. The effect of immunocastration on production performance is welldocumented for both swine and cattle. Although ram lambs used for meat production are often physically castrated, information regarding the potential application of immunocastration in sheep is limited. However, immunocastration may potentially improve the welfare, performance, and meat quality of ram lambs used in commercial meat production systems. The purpose of this review is to compare the application and the effects of immunocastration on male livestock to highlight and motivate the need for further research into its use on ram lambs.

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Section: Cattlementioning

confidence: 75%

Section: Cattlementioning

confidence: 99%

Section: Cattlementioning

confidence: 99%

Section: Cattlementioning

confidence: 99%

See 2 more Smart Citations

Castration of male livestock and the potential of immunocastration to improve animal we

Needham¹,

Lambrechts²,

Hoffman³

2017

SA J. An. Sci.

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“…Impfung eine deutlich geringere Bewegungsaktivität aufwiesen als die Kontrolltiere (Abb. 1, Janett et al, 2012a). *** ** * * *** * * * ** *** ** * **** ** * * ****************** ******* ******* **** ************* **** ***************** *** ****** * * *…”

Section: Involution Des Hodenparenchyms Kann Nach Burdizzokastration unclassified

Die Kastration beim männlichen Kalb und Lamm

Steiner

Janett

2013

Schweizer Archiv für Tierheilkunde

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Local anesthesia is not necessary for this procedure. Ram lambs should be castrated at the age of 14 days or less, at least 10 minutes after local anesthesia with lidocaine, applying a rubber ring. The toxic dose of 4mg lidocaine / kg BW (corresponds to 1 ml lidocaine 2% per lamb of 5kg BW) should not be exceeded. Concurrently, a NSAID (off label use) and Tetanus-serum should be administered systemically. Immunization against GnRH represents an animal-friendly and economically feasible alternative to rubber ring castration. With two immunizations at an interval of 3-4 weeks testicular development can be inhibited for at least 3 months and the onset of puberty clearly delayed. However, a specific vaccine for use in ruminants is currently registered neither in Switzerland nor in Europe.2

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Impacts of Reproductive Technologies on Beef Production in the United States

Dahlen

Larson

Lamb

2013

Current and Future Reproductive Technologies and World Food Production

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Estimations of world population growth indicate that by the year 2050 we will reach nine billion habitants on earth. These estimates impose a tremendous challenge in the current agricultural systems as food supply will need to increase by 100 % in the next 40 years (Food and Agriculture Organization of the United Nations 2009). Beef will be a primary protein source that will assist in meeting the requirements for a portion of the protein in diets of this expanding global populace. Beef is a high-quality protein that contains all essential amino acids for the human body and also contains additional essential nutrients such as iron, zinc, B vitamins, riboflavin, selenium, choline, and conjugated linoleic acid (CLA). Adopting reproductive technologies at greater rates than currently used is a viable method to dramatically enhance production efficiency of beef cattle enterprises.Artificial insemination (AI), estrous synchronization and fixed-time AI (TAI), semen and embryo cryopreservation, multiple ovulation and embryo transfer (MOET), in vitro fertilization, sex determination of sperm or embryos, and nuclear transfer are technologies that are used to enhance the production efficiency of beef operations. In many cases, the development of these technologies is responsible for significant changes to traditional livestock production practices. However, adoption of these technologies appears to has not grown at the same rate in the United States as other formidable beef producing nations. For example, sales of beef semen for AI increased from 3.3 to 11.9 million units between 1993 and 2011 in Brazil, whereas that in the United States has increased from 2.9 to 3.8 million units during the same period. The significant increases in adoption of reproductive technologies in developing countries is likely as a result of the development of practical estrous synchronization and TAI systems that have allowed beef producers the opportunity to eliminate detection of estrus in their AI programs with a high degree of success. In the United States, slow adoption rates of these technologies may result in a future loss of international market share of beef products as other nations take advantage not only of the additional kilogram of beef that can be produced but also the improved quality of beef that can be realized through incorporation of reproductive technologies and resultant genetic improvement. However, current difficulties the US producers have with the incorporation of applied reproductive technologies, such as TAI, MOET, and sex semen, must not be the reason to overlook and incorporate more traditional reproductive technologies such as castration, breeding season management, or weaning. In many cases, beef producers in the United States fail to incorporate these more traditional technologies, which results in a reduction in production efficiency of the US beef industry. This chapter will focus on both traditional and more developed reproductive technologies that will play a role in enhancing future production efficiencies of...

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Vaccination against gonadotropin-releasing factor (GnRF) with Bopriva significantly decreases testicular development, serum testosterone levels and physical activity in pubertal bulls

Cited by 55 publications

References 39 publications

Castration of male livestock and the potential of immunocastration to improve animal we

Castration of male livestock and the potential of immunocastration to improve animal we

Die Kastration beim männlichen Kalb und Lamm

Impacts of Reproductive Technologies on Beef Production in the United States

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