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Stieglitz, Thomas; Beutel, Hansjo ̈rg; Schüettler, Martin; Meyer, J.-U.

doi:10.1023/a:1009955222114

Cited by 302 publications

(101 citation statements)

References 11 publications

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“…[1][2][3] However, pure PI resin suffers from some limitations during its application. For instance, a high friction coefficient and poor resistance to mechanical wear limit its wider application as an insulation material for wire and cable applications.…”

Section: Introductionmentioning

confidence: 99%

Facile preparation of polyimide/graphene nanocomposites via an in situ polymerization approach

et al. 2017

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In this study, to achieve a compatible and good dispersion of graphene in polyimide matrix, we synthesized an aromatic diamine, aniline trimer, as a polymerizable graphene dispersant. Polyimide/graphene nanocomposites with 0.25-2% mass fraction of graphene were prepared by in situ condensation of pyromellitic dianhydride, 4,4 0 -oxydianiline, and aniline trimer (AT) functionalized graphene in DMAc, following subsequent thermal imidization at elevated temperatures. UV-vis and Raman spectroscopy verified the p-p interactions between AT and graphene. The microstructure analysis using XRD, SEM, and TEM were performed to investigate the morphology of graphene in the polyimide matrix. The thermal, mechanical, and tribological properties of polyimide/graphene nanocomposites were investigated by TGA, DMA, and friction and wear tests. In view of the ease of preparation and their superior physical properties over neat polyimide, PI/G composites prepared in this study showed promising applications as wear-resistant and self-lubricating materials.

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Section: Introductionmentioning

confidence: 99%

Facile preparation of polyimide/graphene nanocomposites via an in situ polymerization approach

et al. 2017

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“…Polyimides have previously been used in the field of bio-interfaces in such applications as cuff electrodes and sieve electrodes (Rodriguez et al, 2000;Stieglitz et al, 2002Stieglitz et al, , 2000. Cuff electrodes, which wrap around a nerve trunk, can be used to record sensory signals from peripheral nerves or stimulate motor fibers to activate muscles.…”

Section: Introductionmentioning

confidence: 99%

Flexible polyimide microelectrode array for in vivo recordings and current source density analysis

Cheung

Renaud

Tanila

et al. 2007

Biosensors and Bioelectronics

206

142

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This work presents implantable, flexible polymer-based probes with embedded microelectrodes for acute and chronic neural recordings in vivo, as tested on rodents. Acute recordings using this array were done in mice under urethane anesthesia and compared to those made using siliconbased probes manufactured at the Center for Neural Communication Technology, University of Michigan. The two electrode arrays yielded similar results. Recordings with chronically implanted polymer-based electrodes were performed for 60 days post-surgically in awake, behaving rats. The microelectrodes were used to monitor local field potentials and capture laminar differences in function of cortex and hippocampus, and produced response waveforms of undiminished amplitude and signal-to-noise ratios 8 weeks after chronic implantation. The polymer-based electrodes could also be connected to a lesion current to mark specific locations in the tissue. Current source density (CSD) analysis from the recordings depicted a source-sink-composition. Tissue response was assessed 8 weeks after insertion by immunochemical labeling with glial fibrillary acidic protein (GFAP) to identify astrocytes, and histological analysis showed minimal tissue reaction to the implanted structures.

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“…Devices fabricated with polyimide were appealing because of material's dielectric properties, mechanical flexibility, biocompatibility, and batch fabrication. In earlier investigations by Stieglitz et al, 2 polyimide was found to be reliable in physiological environments as it did not degrade with time and was nontoxic to surrounding cells. Furthermore, polyimide was light weight, conquering the mechanic challenges of the previously considered materials, making it a more ideal choice.…”

Section: Introductionmentioning

confidence: 89%

Biocompatibility of polyimide-based neural interfaces for chronic implant applications

Watkins¹,

Gandhi²,

Rousche³

2007

J Undergrad Research UIC

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Neural interfaces provide functional re-establishment of the central nervous system, as well as accessibility to monitor physiological responses at a cellular and molecular level. An ideal device is electrically, mechanically, and biologically compatible in long-term applications. Reducing the foreign body response and scar tissue formation caused by the surrounding tissue of the implant makes the device most biocompatible, while not hindering the electrical interface of the device. Technological advances in polymer materials are leading to improved designs of neural implants with the utilization of flexible polyimide, which decreases the relative micromotion strain. However, the flexibility of polyimide causes the device to buckle during insertion; therefore a biodegradable polymer, polyglycolic acid (PGA), is added to the polyimide device in order to temporarily enhance the structural rigidity. In this study we detail the successful biocompatibility demonstrated with both uncoated and PGA coated polyimide devices to provide new design strategies for neural implants used in chronic applications.

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Untitled

Cited by 302 publications

References 11 publications

Facile preparation of polyimide/graphene nanocomposites via an in situ polymerization approach

Facile preparation of polyimide/graphene nanocomposites via an in situ polymerization approach

Flexible polyimide microelectrode array for in vivo recordings and current source density analysis

Biocompatibility of polyimide-based neural interfaces for chronic implant applications

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