Abstract:Introduction:The oral route is widely favored for drug delivery due to its simplicity. However, after oral administration, the effectiveness of tizanidine hydrochloride (TZN) is limited due to its low solubility and increased metabolism. The present study investigates the utility of nanostructured lipid carriers (NLCs) as an oral formulation for TZN to boost its therapeutic effectiveness. Materials and Methods: TZN-loaded NLCs were prepared by the solvent evaporation method using glyceryl monostearate and olei… Show more
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