V4-07 Use of Intra-Operative Indocyanine Green and Firefly® Technology to Visualize the “Landmark Artery” for Nerve Sparing Robot Assisted Radical Prostatectomy

Kumar, Anup; Samavedi, Srinivas; Bates, Anthony; Coelho, Rafael; Rocco, Bernardo; Marquinez, Jeff; Jenson, Cathy; Palmer, Kenneth J.; Patel, Vipul

doi:10.1016/j.juro.2015.02.719

Cited by 1 publication

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“…Indocyanine green lymphangiography has also been assessed for sentinel lymph node dissection in radical prostatectomy, cystectomy, and penectomy. [9,11,12] Lastly, ICG may play a role in delineating tumor margins in urological and nonurological radical surgery. [13,14] Despite these potential benefits, the pharmacokinetics of ICG limits its usability in certain scenarios.…”

Section: Introductionmentioning

confidence: 99%

Laser speckle contrast imaging compared with indocyanine green in renal perfusion of a porcine model

Noël¹,

Mascarenhas²,

Nwaiwu³

et al. 2022

Curr Urol

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BackgroundWhen viewed under near-infrared light, indocyanine green (ICG) signal for kidney perfusion can be utilized in partial nephrectomy. Laser speckle contrast imaging (LSCI) uses coherent light to detect perfusion during real-time laparoscopic surgery.Materials and methodsLaser speckle contrast imaging or ActivSight, an imaging sensor adapter, was used during laparoscopy of an anesthetized porcine kidney model. ActivSight's “perfusion mode” and “quantification mode” displayed the blood flow as a heatmap and numerical signal intensity, respectively.ResultsAfter the upper segmental renal artery was clamped, ICG was seen in the lower pole, and LSCI showed low unit (dark color) quantification and perfusion in the upper pole. Indocyanine green was retained in the lower pole after the upper segmental artery was unclamped, and LSCI perfusion was demonstrated in the entire kidney.ConclusionsLaser speckle contrast imaging is a dye-free, repeatable, real-time adjunct for renal parenchymal perfusion assessment applicable to minimally invasive renal surgery to complement the technology of ICG near-infrared fluorescence and advance digital surgery.

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