V.02.2 Endoscopic Ultrasound Guided Radiofrequency Ablation of a Pancreatic Neuroendocrine Tumour (With Video)

EUS-guided Radiofrequency Ablation (EUS-RFA) of Solid Pancreatic Neoplasm Using an 18-gauge Needle Electrode: Feasibility, Safety, and Technical Success

“…Moreover, using percutaneous or EUS guidance, a safe mini-invasive approach can be obtained avoiding laparotomy. To the best of our knowledge, 10 patients underwent pancreatic EUS-RFA with the EUSRA electrode without severe adverse events and with high technical success [5,[18][19][20]. The results of our series confirm the feasibility, safety and local thermal effect of the procedure.…”

“…First, EUS-RFA can be included in multimodality treatment protocols for locally advanced PDAC. Second, EUS-RFA could represent a possible treatment for pancreatic solid lesions in patients unfit for surgery due to comorbidities, or for patients who refuse surgery [19].…”

Critical Topics in the Clinical and Therapeutic Approach to Insulinoma: A Comprehensive Review to Improve Care and Management

“…It is essential to highlight that, within this context, around 90% of insulinomas appear as single lesions, generally benign and small (< 2 cm), which can be located in different regions of the pancreas (MARX M. et al, 2022;YUAN T. et al, 2021). However, between 5% and 10% of these tumors may be associated with Type I Multiple Endocrine Neoplasia, a condition that is related to less favorable prognoses (CRINÒ S.F. et al, 2023).…”

“…Conventional treatment of insulinoma involves surgical resection of the affected pancreatic tissue, an effective intervention, but associated with a significant rate of adverse events (AEs) (CRINÒ S.F. et al, 2023).…”

“…This approach has advantages, such as preserving the endocrine and exocrine function of the pancreas, in addition to reducing the length of hospital stay (NAPLES R. et al, 2022). However, even these minimally invasive techniques are not free from relevant AEs (CRINÒ S.F. et al, 2023).…”