Uveitis in HIV-Infected Patients

Mwanza, Jean-Claude; Kayembe, D. L.

doi:10.1177/112067210101100110

Cited by 15 publications

(13 citation statements)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Notably, none of our participants presented with clinical characteristics suggestive for ocular toxoplasmosis. The high prevalence of herpetic uveitis, mainly VZV, is most likely due to the high herpes virus infection rate in the Mopani district 13 14. Congruent with an earlier study from Congo, demonstrating that 38 of 89 uveitis cases among HIV-infected individuals were VZV induced,13 VZV was the most common viral cause of infectious uveitis in our study.…”

Section: Discussionsupporting

confidence: 75%

“…The high prevalence of herpetic uveitis, mainly VZV, is most likely due to the high herpes virus infection rate in the Mopani district 13 14. Congruent with an earlier study from Congo, demonstrating that 38 of 89 uveitis cases among HIV-infected individuals were VZV induced,13 VZV was the most common viral cause of infectious uveitis in our study. Despite a CMV seroprevalence of 100% among HIV-infected ART-naïve individuals in the Mopani district, we observed only a single case of CMV retinitis.…”

Section: Discussionsupporting

confidence: 75%

See 1 more Smart Citation

Uveitis is predominantly of infectious origin in a high HIV and TB prevalence setting in rural South Africa

et al. 2016

View full text Add to dashboard Cite

show abstract

Section: Discussionsupporting

confidence: 75%

Section: Discussionsupporting

confidence: 75%

Uveitis is predominantly of infectious origin in a high HIV and TB prevalence setting in rural South Africa

et al. 2016

View full text Add to dashboard Cite

show abstract

“…5 Anterior uveitis seems to be a more common presentation of other causes of inflammation of the uveal tract in HIV-positive patients, such as herpes zoster (HZ) ophthalmicus, tuberculosis, CMV infection and toxoplasmosis. 20 Depigmentation of the peripheral retina with preservation of the central visual acuity is a known side effect of dideoxyinosine, 2 seen most commonly in children. 4 Iridocyclitis due to Reiter's syndrome, is another form of uveitis reported to occur more commonly in patients with HIV infection than those without it.…”

Section: Uveitis Due To Other Causesmentioning

confidence: 99%

What you can see in your patient's eyes? Review of ocular manifestations of HIV in HAART era

Nasoodi

Lim²,

Alani³

et al. 2008

Int J STD AIDS

View full text Add to dashboard Cite

The early diagnosis and treatment of ocular disease to prevent morbidity and mortality of patients with human immunodeficiency virus (HIV) is of paramount importance. Since the advent of highly active antiretroviral therapy (HAART), the incidence of ocular complications of HIV has decreased and their manifestations and natural course are also modified. This has been observed in the face of emerging immune recovery, which per se has brought new difficulties in the process of diagnosing and management of the ocular disease. Conditions such as immune recovery uveitis could affect eyes with history of opportunistic disease with a potential to cause vision loss; with this regard, differentiation of the inflammatory process from infective causes is essential. The other sexually contracted diseases are also to be included in this complex picture because of their contribution to the clinical picture and also sharing common routes of transmission with HIV. There is very little doubt that visual deterioration would further deteriorate the already compromised quality of life of this group of patients. In this review, authors wish to provide evidence available in the medical literature around the visual health issues in HIV-infected patients and raise awareness towards the changing pattern of the ocular disease in the HAART era.

show abstract

“…Numerous studies of the pattern of IU have been published, showing similarities and distinct differences in the clinical characteristics, etiologic profile, and course of the disease [3][4][5][6]. Data on IU from developing countries are scarce [3,4,7,8], and there is a lack of studies from the North African and Middle East region [9].…”

Section: Introductionmentioning

confidence: 99%

Clinical characteristics of intermediate uveitis in Tunisian patients

et al. 2010

View full text Add to dashboard Cite

To analyze the pattern of intermediate uveitis (IU) in a referral center in Tunisia, North Africa. A retrospective, descriptive study of 87 consecutive patients (145 eyes) examined at the Department of Ophthalmology of Monastir (Tunisia) from January 1996 to August 2008. All patients underwent an extensive ocular and systemic history, a complete ophthalmic examination, and fluorescein angiography. Standard diagnostic criteria of IU were employed. The mean follow-up period was 43.2 months (range, 4-65 months). The mean age at diagnosis of IU was 29.1 years (range, 5-54 years). The male-to-female ratio was 1:1.6. Both eyes were affected in 58 patients (66.7%). The best-corrected visual acuity at onset of uveitis ranged from light perception to 20/20 (mean, 20/32). The most frequent ocular findings were vitritis (100%), snowballs (53.8%), and retinal vasculitis (28.3%). Concurrent anterior uveitis was noted in 38.6% of affected eyes. Intermediate uveitis was most commonly idiopathic (86.2%). Systemic associations were found in 13.8%; sarcoidosis (9.2%) and multiple sclerosis (2.3%) were the most common systemic diseases. The ocular complications that developed during the follow-up period included cystoid macular edema (39.3%), cataract (31.7%), inflammatory optic disc involvement (26.2%), and glaucoma or ocular hypertension (9%). One hundred-twelve affected eyes (77.2%) had a final visual acuity more than or equal to 20/40. Factors of poor visual outcome were initial VA less than 20/40 (P = 0.00011), CME (P = 0.0016), and vitritis more than 3+ cells (P = 0.023). In a hospital population in Tunisia, intermediate uveitis started frequently at the 3rd decade. This type of uveitis was most commonly idiopathic. Cystoid macular edema and cataract were the most frequent complications. Visual prognosis appeared to be fairly good.

show abstract

Uveitis in HIV-Infected Patients

Abstract: In HIV-infected patients uveitis is frequently associated with opportunistic infections.

Cited by 15 publications

References 17 publications

Uveitis is predominantly of infectious origin in a high HIV and TB prevalence setting in rural South Africa

Uveitis is predominantly of infectious origin in a high HIV and TB prevalence setting in rural South Africa

What you can see in your patient's eyes? Review of ocular manifestations of HIV in HAART era

Clinical characteristics of intermediate uveitis in Tunisian patients

Contact Info

Product

Resources

About